摘要
目的探讨降钙素原(PCT)、白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)联合检测在诊断小儿肺炎中的应用价值。方法选取小儿肺炎患儿85例,根据病原学检查结果分为细菌组57例和非细菌组27例,另选取42例健康体检的正常儿童作为健康组。检测并比较3组PCT、IL-6、hs-CRP水平。比较PCT、IL-6、hs-CRP及三者联合检测阳性率。结果细菌组PCT、IL-6、hs-CRP水平均显著高于非细菌组、健康组,非细菌组PCT、IL-6、hs-CRP水平显著高于健康组(P <0. 05)。细菌组PCT、IL-6、hs-CRP单独检测及三者联合检测阳性率均显著高于非细菌组(P <0. 05)。结论 PCT、IL-6、hs-CRP联合检测能有效诊断小儿肺炎。
Objective To explore the value of combined detection of procalcitonin （PCT）, interleukin-6 （IL-6） and high sensitive C reactive protein （hs-CRP） in the diagnosis of children with infantile pneumonia. Methods Totally 85 children with infantile pneumonia were selected and divided into bacteria group （ n =57） and non-bacterial group （ n =27） according to the results of the pathogenic examination. The 42 normal children were selected as healthy group. The levels of PCT, IL-6 and hs-CRP were detected and compared between the three groups. The positive rates of PCT, IL-6, hs-CRP and combined detection of the three indexes were compared between three groups. Results The levels of PCT, IL-6 and hs-CRP in the bacterial group were significantly higher than those in the non-bacterial group and the healthy group, and the levels of PCT, IL-6 and hs-CRP in non-bacterial group were significantly higher than those in the healthy group （ P 〈0.05）. The positive rates of PCT, IL-6, hs-CRP and combined detection in the bacterial group were significantly higher than those in the non-bacterial group （ P 〈0.05）. Conclusion The combined detection of PCT, IL-6 and hs-CRP has an excellent effect in the diagnosis of children with infantile pneumonia.
作者
邱立东
黄华泥
徐五星
QIU Lidong;HUANG Huani;XU Wuxing(Department of Laboratory,Chibi People′s Hospital,Chibi,Hubei,43730)
出处
《实用临床医药杂志》
CAS
2018年第19期140-142,共3页
Journal of Clinical Medicine in Practice
关键词
降钙素原
白细胞介素-6
超敏C反应蛋白
小儿肺炎
诊断价值
procalcitonin
interleukin-6
high sensitivity C reactive protein
infantile pneumonia
diagnostic value
