摘要
微生物与肿瘤的发生发展密切相关，微生物可通过免疫系统，影响肿瘤的发生发展和转移。本文从肿瘤发展过程中，微生物与巨噬细胞、T细胞、骨髓来源的抑制性细胞和其他免疫细胞的相互作用的关系做一综述。并总结微生物影响的抗肿瘤免疫治疗，提高人们对微生物影响肿瘤机制的全面认识，为肿瘤的预防、免疫治疗新疗法提供参考。
Microbes are closely associated with tumor development. The interactions between mi-crobes and immune system contribute to tumor progression and metastasis. This review focused on the inter-actions between microbes and immune cells （macrophages, T cells, myeloid-derived suppressor cells and other immune cells） in the course of tumor growth, and summarized the roles of microbes in tumor immuno-therapies, aiming to improve the overall understanding of the mechanisms for microbes affecting tumors, and provide ideas for tumor prevention and future immunotherapies.
作者
刘诗雨
李明云
周学东
程磊
Liu Shiyu;Li Mingyun;Zhou Xuedong;Cheng Lei(State Key Laboratory of Oral Diseases,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China（Liu Shiyu,Li Mingyun,Zhou Xuedong,Cheng Lei;Department of Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China（Liu Shiyu,Zhou Xuedong,Cheng Le)
出处
《中华微生物学和免疫学杂志》
CAS
CSCD
北大核心
2018年第10期790-795,共6页
Chinese Journal of Microbiology and Immunology
基金
国家重点研发计划重点专项课题（2017YFC0840100,2017YFC0840107）
