摘要
目的探讨腹腔镜与开腹胆囊切除对胃肠激素、炎症因子和血清淀粉酶的影响。方法以该院住院部于2017年4月—2018年4月收治的72例急性结石胆囊炎患者作为研究对象,观察组患者临床上提供LC治疗,对照组患者临床上提供传统性开腹胆囊切除术治疗,对比临床上的ACC患者进行LC治疗与传统开腹胆囊切除术治疗的疗效。结果观察组患者经LC治疗后,术中时间(75.26±11.36)min、术中出血量(58.32±6.35)mL、肠鸣音术后康复时间(9.36±2.65)h以及住院时间(5.86±1.56)h明显优于对照组,差异有统计学意义(t=3.256、4.325、5.635、3.265,P<0.05)。观察组手术后GAS (130.25±15.54)pg/mL、MTL (208.24±22.15)pg/mL、TNF-α(7.58±1.87)mmol/L、IL-6 (22.56±5.32)mg/L、血清淀粉酶(235.25±19.47)LI/L显著优于对照组,差异有统计学意义(t=3.240、2.563、6.345、2.876、8.894,P<0.05)。结论对于胆囊切除患者,开腹对患者胃肠激素、炎症因子和血清淀粉酶的影响较大,腹腔镜技术具有创伤小恢复快等优势,临床效果满意。
Objective To investigate the effects of laparoscopic and open cholecystectomy on gastrointestinal hormones, inflammatory factors and serum amylase. Methods 72 patients with acute calculous cholecystitis admitted to the hospital from April 2017 to April 2018 were enrolled. The patients in the observation group were clinically provided with LC. The patients in the control group were clinically provided with conventional open cholecystectomy. The treatment was compared with the clinical treatment of ACC patients with LC and traditional open cholecystectomy. Results After treatment with LC, the intraoperative time （75.26±11.36）min, intraoperative blood loss （58.32±6.35）mL, postoperative recovery time of bowel sounds （9.36±2.65）h, and hospitalization time （5.86±1.56）h, significantly better than the control group and was statistically significant（t=3.256, 4.325, 5.635, 3.265, P〈0.05）. GAS （130.25±15.54）pg/mL, MTL （208.24±22.15）pg/mL, TNF-α （7.58±1.87）mmol/L, IL-6 （22.56±5.32）mg/L, serum starch enzyme （235.25±19.47） LI/L after operation, significantly better than the control group, with statistical difference （t=3.240, 2.563, 6.345, 2.876, 8.894, P〈0.05）. Conclusion For patients with cholecystectomy, laparotomy has a greater impact on gastrointestinal hormones, inflammatory factors and serum amylase. Laparoscopic techniques have the advantages of small trauma and quick recovery, and the clinical results are satisfactory.
作者
杜修生
DU Xiu-sheng(Department of General Surgery,Second People＇s Hospital of Heze City,Heze,Shandong Province,274000 China)
出处
《系统医学》
2018年第19期80-82,共3页
Systems Medicine
关键词
腹腔镜
开腹
胆囊切除
胃肠激素
炎症因子
血清淀粉酶
Laparoscopic
Open surgery
Cholecystectomy
Gastrointestinal hormones
Inflammatory factors
Serum amylase
