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β-arrestin2在炎症性肠病中的研究进展 被引量:4

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摘要 炎症性肠病(inflammatory bowel disease,IBD)是一种慢性非特异性的炎症性疾病,可分为溃疡性结肠炎(Ulcerative colitis,UC)和克罗恩病(Crohn,S dis-ease,CD),其发病机制至今尚不十分清楚,但一般认为可能与炎症反应[1]、免疫调节失衡[2]、细胞增殖凋亡等[3]有关。
作者 李慧敏 沈磊
出处 《临床消化病杂志》 2018年第5期322-325,共4页 Chinese Journal of Clinical Gastroenterology
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  • 1Jiyuan Sun, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, TX 77030, United States.CARMA3: A novel scaffold protein in regulation of NF-κB activation and diseases[J].World Journal of Biological Chemistry,2010,1(12):353-361. 被引量:2
  • 2Stefanelli T,Malesci A,Repici A,Vetrano S,Danese S.New insights into inflammatory bowel disease pathophysiology:paving the way for novel therapeutic targets.Curr Drug Targets 2008; 9:413-418. 被引量:1
  • 3Polinska B,Matowicka-Karna J,Kemona H.[The cytokines in inflammatory bowel disease] Postepy Hig Med Dosw (Online) 2009; 63:389-394. 被引量:1
  • 4Li Z,Zhang de K,Yi WQ,Ouyang Q,Chen YQ,Gan HT.NF-kappaB p65 antisense oligonucleotides may serve as a novel molecular approach for the treatment of patients with ulcerative colitis.Arch Med Res 2008; 39:729-734. 被引量:1
  • 5Kizaki T,Izawa T,Sakural T,Haga S,Taniguchi N,Tajiri H,Watanabe K,Day NK,Toba K,Ohno H.Beta2-adrenergic receptor regulates Tog-like receptor4-induced nuclear factor-kappaB activation through beta-arrestin 2.Immunology 2008; 124:348-356. 被引量:1
  • 6Defea K.Beta-arrestins and heterotrimeric G-proteins:collaborators and competitors in signal transduction.Br J Pharmacol 2008; 153 Suppl 1:S298-S309. 被引量:1
  • 7Barki-Harrington L,Rockman HA.Beta-arrestins:multifunctional cellular mediators.Physiology (Bethesda) 2008; 23:17-22. 被引量:1
  • 8DeFea KA.Beta-arrestin multimers:does a crowd help or hinder function? Biochem J 2008; 413:e1-e3. 被引量:1
  • 9Gurevich VV,Gurevich EV,Cleghorn WM.Arrestins as multi-functional signaling adaptors.Handb Exp Pharmacol 2008:15-37. 被引量:1
  • 10Brown MD,Sacks DB.Protein scaffolds in MAP kinase signalling.Cell Signal 2009; 21:462469. 被引量:1

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