摘要
目的研究持续缓慢低效血液透析滤过治疗重症胰腺炎的效果。方法以我院2016年1月～2018年1月我院收治的重症胰腺炎患者64例作为观察研究对象,随机分为常规治疗的对照组(n=32)以及持续缓慢低效血液透析滤过治疗观察组(n=32),比较两组患者的预后效果。结果 (1)观察组白细胞计数恢复正常时间、血淀粉酶、尿淀粉酶恢复时间以及住院天数以及治疗后72h APACHEⅡ评分均小于对照组,差异有统计学意义(P <0.05)。(2)两组治疗后PO2、PaO2/FiO2较治疗前有所提高,但观察组高于对照组,两组患者IL-6、TNF-α等炎性因子水平有所降低,但观察组更低,差异有统计学意义(P <0.05);(3)观察组治疗总有效率高达93.75%高于对照组75.00%,差异有统计学意义(P <0.05)。结论持续缓慢低效血液透析治疗重症胰腺炎效果更佳,能有效改善患者临床症状,值得临床推广。
Objective To investigate the effect of continuous slow and ineffective hemodialysis on severe panereatitis. Methods Sixty-four patients with severe acute panereatitis treated in our hospital from January 2016 to January 2018 were randomly divided into control group and observation group,with 32 cases in each group.The control group was given conventional treatment,while the observation group was given continuous slow and low effective hemodialysis.The prognostic effects of the two groups were compared. Results （1） The recovery time of normal white blood cell count,serum amylase,urinary amylase recovery time,length of hospital stay and APACHE II score at 72 hours after treatment were all lower in the observation group than in the control group （/9 〈 0.05）.（2）PO2 and PaOJ FiO2 increased after treatment in the two groups,but the observation group was higher than the control group.The level of IL-6,TNF- ot and other inflammatory factors decreased in the two groups,but the observation group was more The difference was statistically significant （P 〈 0.05）.（3）The total effective rate in the observation group was 93.75% higher than that in the control group 75.00%.The difference was statistically significant （P 〈 0.05）. Conclusion Continuous slow and low effect hemodialysis has a better effect on severe acute panereatitis,whieh can effectively improve the clinical symptoms of patients,and is worthy of clinical promotion.
作者
林仰东
罗正超
杨亚东
LIN Yangdong;LUO Zhengchao;YANG Yadong(Poai hospital of Zhongshan,Zhongshan 528400,China)
出处
《中国医药科学》
2018年第19期234-236,共3页
China Medicine And Pharmacy
关键词
持续缓慢低效血液透析滤过
重症胰腺炎
预后效果
炎性因子
Slow and slow effective hemodialysis
Severe pancreatitis
Prognosis effect
Inflammatory factors
