摘要
目的比较炎琥宁与α-干扰素治疗小儿上呼吸道感染的效果。方法 68例小儿上呼吸道感染患儿,通过电脑完全随机分组法分为常规组与研究组,每组34例。常规组患儿在常规对症处理基础上接受α-干扰素治疗,研究组患儿在常规对症处理基础上接受炎琥宁治疗。观察比较两组患儿的治疗效果、不良反应发生情况以及体温恢复至正常时间。结果研究组临床治疗总有效率94.12%显著高于常规组的76.47%,差异具有统计学意义(P<0.05)。研究组不良反应发生率2.94%明显低于常规组的17.65%,差异具有统计学意义(P<0.05)。研究组患儿体温恢复至正常时间(1.4±0.2)d明显短于常规组的(3.5±0.5)d,差异具有统计学意义(t=22.738, P<0.05)。结论相比于α-干扰素而言,小儿上呼吸道感染患儿行炎琥宁治疗的效果更为显著,可帮助患儿尽快恢复至正常体温,且用药方案安全性较高,值得临床借鉴普及。
Objective To compare the effect of Dehydroandrographolide Succinate and alphainterferon in the treatment of children with upper respiratory tract infection. Methods A total of 68 children with upper respiratory tract infection were divided into conventional group and research group by computer completely random grouping method, 34 cases in each group. Children in the conventional group received alpha-interferon treatment on the basis of conventional symptomatic treatment, children in the research group received Dehydroandrographolide Succinate treatment on the basis of conventional symptomatic treatment. The therapeutic effect, adverse reactions and body temperature returned to normal time between the two groups were compared. Results The total effective rate of the research group was 94.12%, which was significantly higher than 76.47% of the conventional group, the difference was statistically significant（P0.05）. The incidence of adverse reactions in the research group was 2.94%, which was significantly lower than 17.65% in the conventional group, the difference was statistically significant（P0.05）. The body temperature returned to normal time of the research group was（1.4±0.2） d, which was significantly shorter than（3.5±0.5） d of the conventional group, the difference was statistically significant（t=22.738, P0.05）. Conclusion Compared with alpha-interferon, Dehydroandrographolide Succinate is more effective in the treatment of children with upper respiratory tract infection. It can help children recover to normal body temperature as soon as possible, and the drug regimen is safer. It is worthy of clinical reference and popularization.
作者
郭旭丽
GUO Xu-li(Qufu People＇s Hospital of Shandong Province,Qufu 273100,China)
出处
《中国实用医药》
2018年第28期83-85,共3页
China Practical Medicine
关键词
炎琥宁
Α-干扰素
小儿
上呼吸道感染
效果
Dehydroandrographolide Succinate
Alpha-interferon
Children
Upper respiratory tractinfection
Effect
