摘要
目的探讨右美托咪定应用在ICU呼吸衰竭患者行ICU无创机械通气的治疗效果及安全性。方法方便选取2016年1月—2018年1月间在该院ICU进行住院治疗患有呼吸衰竭并进行无创呼吸机治疗的80例患者,分为观察组和对照组,各40例,观察组患者给予右美托咪定镇静;对照组患者无镇静,记录并对比两组相关疗效指标及不良事件情况。结果观察组在T2时心率平均为(83.7±13.9)次/min,呼吸频率平均为(15.2±7.4)次/min,与对照组比较,心率、呼吸频率明显下降(t=7.825,P<0.05)。对照组患者转为有创呼吸机机械通气患者(10例)明显多于观察组(3例),差异有统计学意义(t=6.889,P<0.05)。结论右美托咪定应用于ICU无创机械通气患者治疗呼吸衰竭具有明显的疗效,同时右美托咪定镇静具有减少躁动及呼吸机带来的不适的优点。
Objective To investigate the therapeutic effect and safety of dexmedetomidine in non-invasive mechanical ventilation in patients with ICU respiratory failure. Methods From January 2016 to January 2018 Patients of 80 case hospitalized with ICU in the hospital for respiratory failure and non-invasive ventilator were convenient selected and enrolled. The patients in the observation group were divided into the observation group and the eontrol group,eaeh with 40 ease. The patients in the observation group were given dexmedetomidine sedation. The patients in the eontrol group were not sedated. Compare the two groups of related effieaey indieators and adverse events. Results The heart rate of the observation group was （83.7±13.9） beats/min at T2, and the respiratory rate was （15.2±7.4） beats/min. The heart rate and respiratory rate were significantly lower than those of the control group （t=7.825, P〈0.05）. The patients in the control group were significantly more likely to have mechanical ventilation （10 cases） than the observation group （3 cases）, and the difference was statistically significant （t=6.889, P〈0.05）. Conclusion Dexmedetomidine is effective in the treatment of respiratory failure in patients with non-invasive mechanical ventilation in ICU. Simultaneous dexmedetomidine sedation has the advantage of reducing the discomfort caused by agitation and ventilator.
作者
刘丽诗
LIU Li-shi(Department of Critical Care Medicine,Wuxi Second People＇s Hospital,Nanjing Medical University,Wuxi,Jiangsu Province,214000 China)
出处
《中外医疗》
2018年第27期144-146,共3页
China & Foreign Medical Treatment
关键词
右美托咪定
无创呼吸机
ICU
呼吸衰竭
Dexmedetomidine
Non-invasive ventilator
ICU
Respiratory failure
