摘要
目的探讨子宫切除术与子宫动脉栓塞术对子宫肌瘤患者卵巢功能的影响。方法 102例子宫肌瘤患者,按照随机数字表法分为对照组和研究组,各51例。对照组采用子宫切除术治疗,研究组采用子宫动脉栓塞术治疗。比较两组手术后卵巢排卵功能恢复情况以及手术前后生殖激素水平变化情况。结果对照组3个月内卵巢排卵功能恢复12例(23.53%),研究组术后3个月内卵巢排卵功能恢复32例(62.75%);研究组卵巢排卵功能恢复率明显高于对照组,差异有统计学意义(P<0.05)。两组患者术前血清卵泡生成激素(FSH)、黄体生成激素(LH)、雌二醇(E2)水平比较差异无统计学意义(P>0.05);研究组术后6、12、24个月血清FSH、LH、E_2水平均显著优于对照组,差异有统计学意义(P<0.05)。结论子宫肌瘤患者采用子宫动脉栓塞术治疗有利于患者卵巢排卵功能快速恢复,并能显著促使血清FSH、LH、E_2水平降低,改善临床状况,预后效果良好。
Objective To investigate the influence of hysterectomy and uterine artery embolization on ovarian function in patients with uterine fibroids. Methods A total of 102 patients with uterine fibroids were divided into control group and research group according to the random number table method, 51 cases in each group. The control group was treated with hysterectomy, the research group was treated with uterine artery embolization. The recovery of ovarian function after surgery and the changes of reproductive hormones before and after surgery between the two groups were compared. Results Ovarian ovulation function recovered in 12 cases（23.53%） in the control group within 3 months after surgery, and 32 cases（62.75%） in the research group within 3 months after surgery, the recovery rate of ovarian ovulation function in the research group was significantly higher than that in the control group, the difference was statistically significant（P〈0.05）. There were no significant differences in the serum follicle stimulating hormone（FSH）, luteinizing hormone（LH） and estradiol（E2） between the two groups before surgery（P〉0.05）. The serum FSH, LH and E2 levels at 6, 12 and 24 months after surgery in the research group were significantly better than those in the control group, the differences were statistically significant（P〈0.05）. Conclusion Uterine artery embolization is beneficial to the recovery of ovarian ovulation function in patients with uterine fibroids, and can significantly reduce the serum levels of FSH, LH and E2, improve clinical conditions, and has a good prognosis.
作者
关宝星
张发林
钟沛文
朱敏珊
GUAN Bao-xing;ZHANG Fa-lin;ZHONG Pei-wen(Department of Obstetrics and Gynecology,The First People＇s Hospital of Foshan City,Foshan 528000,China)
出处
《中国实用医药》
2018年第27期32-34,共3页
China Practical Medicine
基金
子宫动脉末梢栓塞与主干栓介入治疗对卵巢功能的影响对比研究(项目编号:2015AB00296)
关键词
子宫切除术
子宫动脉栓塞术
子宫肌瘤
卵巢功能
Hysterectomy
Uterine artery embolization
Uterine fibroids
Ovarian functio
