摘要
目的探讨不同类型静坐不能的临床表现、可能发病机制和治疗方法。方法与结果共3例静坐不能患者,例1诊断为急性静坐不能、药源性帕金森综合征、缺铁性贫血,停用奥氮平,予普萘洛尔、阿普唑仑、苯海索和补铁治疗后好转;例2诊断为迟发性静坐不能、迟发性运动障碍,逐渐减停利培酮、加用阿普唑仑后好转;例3诊断为帕金森病静坐不能,继续予抗帕金森病药多巴丝肼、司来吉兰、普拉克索,加用阿普唑仑、普萘洛尔后好转。结论不同类型静坐不能的治疗方法各异,临床应根据不同类型进行针对性治疗。
Objective To explore the clinical presentations,probable pathogenesis and therapy of different types of akathisia.Methods and ResultsThere were 3 cases of akathisia in this report.The diagnosis of Case 1 was acute akathisia,drug-induced parkinsonism,and iron-deficiency anemia,and the symptoms were relieved after the patient stopped taking olanzapine and was treated with propranolol,alprazolam,benzhexol and iron supplementation.The diagnosis of Case 2 was tardive akathisia and tardive dyskinesia.After risperidone was gradually reduced and alprazolam was added,the symptoms were improved.The diagnosis of Case 3 was akathisia in Parkinson’s disease（PD）.After alprazolam and propranolol were added,while anti-PD drugs（levodopa and benserazide,selegiline and pramipexole）continued to be applied,the symptoms were alleviated.ConclusionsWhen akathisia is treated,its type should be distinguished firstly,and then the treatment should be given according to different types.
作者
王磊
汪明玉
吴金龙
李昀
钟池
WANG Lei;WANG Ming-yu;WU Jin-long;LI Yun;ZHONG Chi(Department of Neurology,Weifang People＇s Hospital,Weifang 261000,Shandong,China;Department of Neurology,Yidu Central Hospital,Weifang 262500,Shandong,China)
出处
《中国现代神经疾病杂志》
CAS
北大核心
2018年第9期688-691,共4页
Chinese Journal of Contemporary Neurology and Neurosurgery
基金
山东省医药卫生科技发展计划项目(项目编号:2014WS0266)~~
关键词
精神运动性激动
抗精神病药
Psychomotor agitation
Antipsychotic agents
