摘要
A general and efficient coupling of aryl bromides with diethyl malonate is presented. The reaction provided the α-arylated diethyl malonates in moderate to good yields with a low loading of CUC12（5%, molar fraction） and 8-hydroxyquinoline（5% , molar fraction）. This method has good compatibility for a wide range of aryl bromides.
A general and efficient coupling of aryl bromides with diethyl malonate is presented. The reaction provided the α-arylated diethyl malonates in moderate to good yields with a low loading of CUC12（5%, molar fraction） and 8-hydroxyquinoline（5% , molar fraction）. This method has good compatibility for a wide range of aryl bromides.
基金
Supported by the National Natural Science Foundation of China（Nos.21572215, 21602215）.
