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急性脑梗死与高同型半胱氨酸的相关性分析 被引量:4

Correlation between acute cerebral infarction and hyperhomocysteine
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摘要 目的研究高同型半胱氨酸和急性脑梗死之间的相关性。方法选取2014年1月至2017年12月我院住院治疗80例急性脑梗死患者为研究组,同时选取同期80例健康体检患者为对照组,比较2组空腹的血液黏度、红细胞沉降率、纤维蛋白原指标及同型半胱氨酸水平,以及各组段率对比。结果研究组的同型半胱氨酸水平(23.8±5.7)μmol/L,高于对照组的(10.2±2.3)μmol/L,差异有统计学意义(P <0.05),且研究组中的男女性患者的同型半胱氨酸分别高于对照组的男女性患者,多因素Logistic回归分析结果示高同型半胱氨酸是脑梗死的主要危险因素。结论积极预防和治疗高同型半胱氨酸血症,可有效减少脑梗死的复发。 Objective To study the correlation between hyperhomocysteine and acute cerebral infarction.Methods Eighty patients with acute cerebral infarction in our hospital were selected as study group and 80 healthy people as control group in the same period. The fasting blood viscosity and erythrocyte sedimentation rate were compared between the two groups. The fibrinogen index, homocysteine level and segment rate of each group were compared.Results The homocysteine level in the study group was (23.8±5.7)μ mol/L, which was higher than that in the control group (10.2±2.3)μmol/L, ( P 〈0.05), and the homocysteine level in the study group was higher than that in the control group. Multivariate logistic regression analysis showed that homocysteine was the main risk factor for cerebral infarction.Conclusion Active prevention and treatment of hyperhomocysteinemia can effectively reduce the recurrence of cerebral infarction.
作者 郝绍江 Hao Shaojiang(Department of Neurology,the Frist Hospital of Yulin City,Shaanxi 718000,China)
出处 《山西医药杂志》 CAS 2018年第20期2398-2399,共2页 Shanxi Medical Journal
关键词 高半胱氨酸 脑梗死 相关性分析 Homocysteine Brain infarction Correlation analysis
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