摘要
微小脲原体(Ureaplasma parvum,UP)与解脲脲原体(Ureaplasma urealyticum,UU)作为条件致病菌常常寄居于泌尿生殖道中。最近研究提出UP感染可以引起严重的临床相关疾病,引起UP致病的主要因素有:多带抗原(MBA)、磷脂酶A、磷脂酶C、IgA蛋白酶、脲原体尿素酶和水平基因转移(HGT),但其诱发临床疾病的具体发病机制尚不明确。因此,对UP感染致病机制的相关研究已成为目前研究的焦点,进而也为临床诊断和治疗提供了重要的参考价值。
Ureaplasma parvum（UP） and Ureaplasma urealyticum are considered to be opportunistic pathogens in the urogenital tract. Recent studies suggest that UP can cause serious diseases. The main factors leading to UP disease include： MBA（multiple antigen）,phospholipase A,phospholipase C,IgA protease,urea urease and horizontal gene transfer（HGT）,but the exact pathogenesis is not clear. Therefore,the research on the pathogenic mechanism of UP infection has become the focus,and it also provides important reference for clinical diagnosis and treatment.
作者
赵红英
汪五清
ZHAO Hongying;WANG Wuqing(Department of Dermatology,MinhangHospital of Fudan University,Shanghai 201199,China;Chinese Medicine Hospital in Juxian,Rizhao 276500,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2018年第10期1195-1198,共4页
The Chinese Journal of Dermatovenereology
关键词
微小脲原体
致病因素
进展
Ureaplasma parvum
Pathogenic factors
Progress
