摘要
目的探讨经鼻双水平正压通气模式(DuoPAP)在足月儿急性呼吸窘迫综合征拔管后应用的临床效果。方法将50例足月儿急性呼吸窘迫综合征患儿随机分为对照组及观察组,均予控制原发病,防治出血、感染,保护脏器及维持水、电解质、酸碱平衡等,达到撤机标准后予拔管,观察组在治疗好转拔管后,使用Duo PAP治疗,对照组治疗好转拔管后,使用HHFNC(高流量湿化氧疗)治疗,比较2组疗效。结果观察组经拔管予DuoPAP治疗后,无创通气时间、需要应用气管插管机械通气例数、呼吸暂停例数均较对照组减少(P均<0.05)。结论足月急性呼吸窘迫综合征患儿拔管后使用Duo PAP组较拔管后使用HHFNC组的无创通气时间减少,需再次插管上呼吸机例数减少,且发生呼吸暂停等不良反应少。
Objective To investigate the clinical effect of nasal doublelevelpositive pressure ventilation （DuoPAP） after extubation in terminfants with acute respiratory distress syndrome. Methods Fifty patientswith acute respiratory distress syndrome were divided into control groupand observation group. All patients were treated with comprehensivetherapy,including the control of primary disease, prevention and treatmentof bleeding, infection control, respiratory management, protection of organfunction, maintenance of water, electrolytes, acid-base balance, blood sugar,blood pressure, plasma or gamma globulin support. After the weaningstandard to extubation, observation group use DuoPAP after extubation,control group use of HHFNC （high-dose wet oxygen therapy） treatment.Then clinical efficacy between the two groups were compared. Results In the observation group, the number of patients with endotracheal intubationand the number of apnea were reduced compared with the control groupafter extubation to DuoPAP treatment （P 〈 0.05）. Conclusion The use ofDuoPAP group after extubation compared with the HHFNC group couldsignificantly reduce the noninvasive ventilation time in the children withacute respiratory distress syndrome after extubation, need to re-intubatethe ventilator to reduce the number of cases, and there were few adversereactions such as apnea..
作者
林多华
肖厚兰
孙世兰
颜陶
王惠莲
LIN Duohua;XIAO Houlan;SUN Shilan;YAN Tao;WANG Huilian(Department of Pediatrics,People＇s Hospital of Gaoming District,FoshanCity,Guangdong Province,Foshan Guangdong 528500,China)
出处
《中国卫生标准管理》
2018年第19期57-59,共3页
China Health Standard Management
基金
2015年佛山市自筹经费类科技计划项目(2015AB001004)
关键词
经鼻
双水平通气
足月儿
急性呼吸窘迫综合征
拔管后
应用
nasal
double-level ventilation
term infant
acute respiratorydistress syndrome
after extubation
application
