摘要
目的分析高血压患者摄盐量与早期肾损害及颈动脉硬化的关系。方法选取2017~2018年在本科住院的高血压患者168例作为研究对象,测24小时尿钠,推算摄盐量,测尿微量白蛋白并行颈动脉彩超检查,用单因素方差分析研究摄盐量与早期肾损害及颈动脉硬化的关系。结果根据24小时尿钠排泄量将患者分为3组,<92.3 mmol组48例,92.3~184.6 mmol组80例,>184.6 mmol组40例。(1)随摄盐量增高,3组患者收缩压及舒张压增高(P<0.05)。(2)随摄盐量升高,3组患者尿微量白蛋白升高(P<0.05)。(3)根据颈动脉彩超分为正常、颈动脉硬化及轻度狭窄(<50%)、重度狭窄及闭塞(>50%)3组,3组尿钠水平比较差异无统计学意义。结论随摄盐量增加与血压升高及早期肾损害有关。
Objective To analyze the relationship between salt intake and early renal damage, and between carotid atherosclerosis in patientswith hypertension. Methods 168 patients with high blood pressure hospitalized in our department in 2017-2018 were selected. 24 hours of urine sodium（positive correlation with salt intake）, urine microalbumin and carotid artery Doppler ultrasound were measured. The relationship between saltintake and early renal damage, and between carotid artery disease and was studied by single factor variance analysis. Results According to 24 hoursurinary sodium excretion, the patients were divided into three groups, 48 in group less than 92.3 mmol, 80 in group 92.3-184.6 mmol, and 40 ingroup above 182.6 mmol. ①With the increase of salt intake, systolic blood pressure and diastolic blood pressure increased（P〈0.05）.②With the increaseof salt intake, microalbuminuria increased（P〈0.05）. ③According to carotid artery color Doppler ultrasound, it was divided into threegroups： normal, carotid artery sclerosis and mild stenosis （〈50%）, severe stenosis and occlusion （〉50%）. There was no statistical difference in thelevel of sodium urine in the three groups. Conclusion Increase of salt intake is related to the increase of blood pressure and early renal damage.
作者
孙蔚雯
商丽华
王晶
张晗
SunWeiwen;Shang Lihua;Wang Jing;Zhang Han(Heart center,Beijing Huaxin Hospital,Beijing,100016,China)
出处
《当代医学》
2018年第28期57-59,共3页
Contemporary Medicine
关键词
24小时尿钠
摄盐量
早期肾损害
颈动脉硬化
24 hours urine sodium
Salt intake
Early renal damage
Carotid atherosclerosis
