摘要
目的探讨扫频源前节相干光层析成像术(ss-AS.OCT)与超声生物显微镜(UBM)测量前房深度及房角参数结果的一致性°方法前瞻性研究°选取2016年11至12月在首都医科大学附属北京同仁医院北京同仁眼科中心就诊的单纯老年性白内障患者45例(45只眼),男性23例,女性22例,年龄(5l±19)岁°分别用SS-AS-OCT和UBM测量其前房深度及鼻、颞、上、下4个方位的房角参数,包括距巩膜突500Ixm的房角开放距离(AOD500)和小梁网.虹膜夹角(T1A500)°采用配对样本t检验比较两种仪器前房深度、AOD500和TIA500的测量结果,采用Pearson直线相关分析法分析两种仪器测量结果的相关性,采用Blant.Ahman分析评价两种仪器测量结果的一致性°结果SS.AS-OCT和UBM测得的前房深度分别为(2.750±0.544)mm和(2.775±0.531)mm,差异有统计学意义(t=2.109,P=0.040),二者测量结果呈正相关(r=0.989,P〈0.001)°SS.AS.OCT与UBM对鼻、颞、上、下4个方位的AOD500和TIA500测量结果差异均有统计学意义fAOD500:SS.AS—OCT检测值分别为(0.451±0.201)mm、(0.499-0.229)mm、(0.390±0.215)mm、(O.441±0.226)mm,uBM检值分别为(0.421±0.194)mm、(0.465±0.207)mm、(0.355±0.208)mm、(0.423±0.215)film,二者比较的t值分别为4.262、4.350、5.355、4.415;TIA500:SS.AS-OCT检测值分别为39.587°±14.6980、42.149°±14.138°、36.482°±15.8870、38.504°±14.805°,UBM检测值分别为36.944°±13.7900、40.289°±13.0410、35.6000±15.215°、36.8180±14.93lo,二者比较的t值分别为5.131、4.658、4.174、5.731;均P〈0.001],且二者测量结果呈正相关(AOD500:r值分别为0.971、0.975、0.979、0.973;TIA500:r值分别为0.972、0.957、0.956、0.970;均P〈0.001)°Blant.Ahman分析显示两种测量方
Objective To explore the difference and agreement in the measurement of anterior chamber depth (ACD) and anterior chamber angle data in age-related cataract patients between swept source anterior segment optical coherence tomography (SS-AS-OCT) and ultrasound biomieroseopy (UBM). Methods A prospective study. Forty-five eyes from 45 age-related cataract patients were selected at Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University from November to December 2016. There were 23 males and 22 females aged (51_+19) years. SS-AS -OCT and UBM were used to measure the ACD, angle opening distance (AOD 500) and trabeeular-iris angle (TIA 500). The paired samples t-test and Pearson linear correlation were used for statistical analysis, and the Bland-Altman analysis was used to evaluate the t consistency of the two tools. Results The ACD measured bySS-AS-OCT and UBM was (2.750-0.544) mm and (2.775-0.531) mm, respectively, the difference was statistically significant (t=2.109, P=0.040), and the measurement results were positively correlated (r=0.989, P〈0.001). In the nasal, temporal, upper and lower positions, the AOD 500 and TIA 500 values measured by SS-AS-OCT and UBM had a significant difference [AOD 500:(0.451±0.201) mm vs. (0.421 ±0.194) ram, (0.499±0.229) mm vs. (0.465±0.207) ram, (0.390±0.215) mm vs. (0.355±0.208) mm, (0.441±0.226) mm vs. (0.423+0.215) ram, t=4.262, 4.350, 5.355, 4.415; TIA 500: 39.587±14.698°vs. 36.944±13.790°, 42.149±14.138%s. 40.289±13.041°, 36.482±15.887°vs. 35.600±15.215°, 38.504±14.805°vs. 36.818±14.931°, t= 5.131, 4.658, 4.174, 5.731; all P〈0.001] and a significant linear eorrelation (AOD 500: r=0,971, 0.975, 0.979, 0.973;TIA 500: r=0.972, 0.957, 0.956, 0.970; all P〈0.001). The Bland-Altman method showed that the two modalities had comparable results for the ACD, AOD 500 and TIA 500 (2.22%- 6.67% of the measured value outside the 95% consistency boundar
作者
沈琳
王霄娜
李栋军
王子杨
陈伟
赵琦
李逸丰
崔蕊
杨文利
Shen Lin;Wang Xiaona;Li Dongjun;Wang Ziyang;Chen Wei;Zhao Qi;Li Yifeng;Cui Rui;Yang Wenli(Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Ophthalmology & Visual Sciences Key Lab.,Beijing 100730,China)
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2018年第9期678-682,共5页
Chinese Journal of Ophthalmology
关键词
白内障
前房
体层摄影术
光学相干
显微镜检查
声学
Cataract
Anterior chamber
Tonlography
optical coherence
Microscopy
acoustic