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一起由诺如病毒引起的感染性腹泻疫情的流行病学调查 被引量:8

Epidemiological Investigation of an Outbreak of Infectious Diarrhea Caused by Norovirus
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摘要 目的调查分析某驻穗部队一起感染性腹泻的流行病学特征,明确事件发生原因,为预防和控制疫情提供参考。方法采用现场流行病学调查方法了解疫情暴发情况及可疑传播途径,采用实时荧光定量PCR方法对患者样本及食品、环境样品进行病原体检测。结果该单位56名人员中有18名官兵发病,罹患率为32.1%。主要症状表现为腹泻(72.2%)和呕吐(61.1%)。实验室检测发现,18例患者的粪便或肛拭子样本中有15例诺如病毒阳性(83.3%)。患者中吃白切鸡的人数比例(66.7%)显著高于未发病人群(13.2%)(P<0.01)。结论结合流行病学调查和实验室检测结果,可以判定本次事件是一起由诺如病毒引起的感染性腹泻暴发。在采取了消毒、隔离、食品卫生监督及健康教育等处置措施后,未出现新发病例,疫情得到控制。 Objective To investigate the epidemiological characteristics and possible causes of an outbreak of infectious diarrhea and provide reference for disease prevention and control. Methods A field epidemiological survey and real-time quantitative PCR were used to investigate the epidemic situation and detect the pathogens in the samples of patients or the environment,respectively.Results Eighteen of the fifty-six members of the unit developed symptoms of gastroenteritis. The attack rate was 32.1%. The observed symptoms were mostly diarrhea(72.2%) and vomiting( 61.1%). Laboratory tests found that fifteen of the eighteen patients with fecal or anal swab were positive for norovirus( 83.3%). The percentage of patients who had eaten sliced boiled chicken (66.7%) was significantly higher than that in the control group( 13.2%)( P 0.01). Conclusion Based on the epidemiological survey and laboratory test results,it could be concluded that this event was an outbreak of infectious diarrhea caused by norovirus. After taking appropriate measures,such as disinfection,isolation,food hygiene supervision and health education,the epidemic was effectively controlled without new occurrence.
作者 李代波 于德宪 严华成 周志坚 银涛 刘乐斌 LI Daibo;YU Dexian;YAN Huacheng;ZHOU Zhijian;YIN Tao;LIU Lebin(Center for Disease Control and Prevention of Guangzhou Military Command,Guangzhou 510507,China)
出处 《解放军预防医学杂志》 CAS 2018年第8期963-966,共4页 Journal of Preventive Medicine of Chinese People's Liberation Army
基金 艾滋病和病毒性肝炎等重大传染病防治国家重大科技项目(No.2013ZX10004203-001-009)
关键词 诺如病毒 感染性腹泻 流行病学调查 norovirus infectious diarrhea epidemiological survey
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