摘要
目的探讨超选择性前列腺动脉栓塞(PAE)联合经尿道前列腺切除术(TURP)治疗重度前列腺增生(前列腺体积〉80ml)的安全性及疗效。方法回顾性分析2015年3月至2017年6月收治的40例重度前列腺增生且药物治疗无效患者的临床资料。其中联合组(PAE+TURP)18例,年龄60-88岁,平均(75.0±8.7)岁;前列腺体积83-145ml,平均(111.0±23.3)ml;术前国际前列腺症状评分(IPSS)(25.2±3.6)分,生活质量评分(QOL)(5.1±1.0)分,最大尿流率(Qmax)(6.4±2.3)ml/s,残余尿量(PVR)(107.7±32.6)ml。TURP组22例,年龄62-85岁,平均(76.0±6.9)岁;前列腺体积80-150ml,平均(107.5±27.4)ml;IPSS(24.3±4.2)分,QoL(4.9±0.9)分,Qmax(6.7±2.2)ml/s,PVR(106.6±32.2)ml。比较两组的手术时间、术中出血量、切除腺体组织重量及切除效率、术后持续膀胱冲洗时间及留置尿管时间、IPSS、QoL、Q。。和PVR等指标,以及术后并发症发生情况。结果联合组和TURP组在手术时间[(75.8±25.1)rain与(103.2±27.7)min]、术中出血量[(122.8±33.9)ml与(447.6±36.0)m1]、前列腺组织切除重量[(99.9±24.2)g与(82.9±15.5)g]及效率[(76.9±20.7)g/h与(41.7±14.2)g/h]、术后持续膀胱冲洗时间[(1.4±0.5)d与(2.4±0.8)d]及留置尿管时间[(2.2±0.4)d与(3.4±0.6)d]等方面比较差异均有统计学意义(P〈0.05)。联合组术后无再次出血和二次电切病例,发生暂时性尿失禁2例,泌尿系感染1例。TURP组术后发生再次出血3例,二次电切3例,暂时陛尿失禁4例,泌尿系感染2例。术后随访1年,联合组和TURP组的IPSS评分分别为(6.7±1.5)分和(6.9±1.5)分,QOL评分分别为(2.3±0.5)分和(2.3±0.6)分,Qmax分别为(15.6±2.3)ml/s�
Objective To explore the safety and efficacy of super-selective prostate artery embolization (PAE) combined with TURP ( transurethral resection of prostate) as an alternative method for patients with severe large BPH ( 〉 80 ml). Methods From March 2015 to June 2017,a total of 40 patients with large benign prostatic hyperplasia who failed in medical treatment were selected for PAE combined with TURP ( 18 cases) and TURP (22 cases). In the PAE combined with TURP group, the mean age was (75.0±8.7) years ( ranging 60 - 88 years) and the mean prostatic volume was ( 111.0 ± 23.3 ) ml, ranged from 83 to 145 ml ). The international prostate symptom score ( IPSS), quality of life ( QOL), maximal urine flow rate ( Qmax ) and postvoid residual urine (PVR) were ( 25.2 ± 3.6), ( 5.1 ± 1.0), ( 6.4 ± 2.3 ) ml/s and ( 107.7± 32.6) ml, respectively. In the TURP group, the mean age was ( 76.0 ± 6.9 ) years ( ranging 62 -85 years) and the mean prostatic volume was (107.5 ± 27.4) ml, ranged from 80 to 150 nd). The IPSS, QOL, Q and PVR were(24.3 ± 4.2 ), (4.9 ± 0.9 ), ( 6.7 ± 2.2 ) ml/s and ( 106.6 ± 32.2 ) ml, respectively. Clinical data of all of patients were analyzed retrospectively, including operative time, estimate blood loss,weight and efficacy of resected tissue, time of continuous bladder iwigation and catheterization, IPSS, QOL, PVR, Q and postoperative complications. Results There were significant differences in the operative time [ (75.8 ± 25.1 ) rain vs. ( 103.2 ± 27.7) min ~, estimate blood loss [ ( 122.8±33.9) ml vs. (447.6 ± 36.0) ml ], weight of resected tissue [ (99.9 ± 24.2 ) g vs. ( 82.9 ±15.5 ) g ], efficacy of resected tissue [ (76.9 ±20.7 ) g/h vs. (41.7± 14.2) g/h I, continuous bladder irrigation time [ ( 1.4± 0.5 ) d vs. (2.4 ± 0.8 ) d ] and catheterization time [ (2.2 ± 0.4) d vs. (3.4 ±0.6) d ] between PAE combined TURP group and TURP grou
作者
吕磊
黄韬
高晓玲
章传华
黄遂斌
Lyu Lei;Huang Tao;Gao Xiaoling;Zhang Chuanhua;Huang Suibin(Department of Urology,Wuhan NO.1 Hospital,Hubei Wuhan 430030,China)
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2018年第9期675-678,共4页
Chinese Journal of Urology
基金
国家自然科学基金(81502204)
湖北省自然科学基金(2014CFB399)
关键词
良性前列腺增生
前列腺动脉栓塞
下尿路症状
Benign prostatic hyperplasia
Prostatic artery embolization
Low urinary tract symptoms