摘要
目的探讨细颗粒物(fine particulate matters,PM2.5)暴露对二尖瓣EF斜率降低检出率的影响。方法选择同期体检的开滦集团员工,已确诊为尘肺Ⅰ期者为暴露组,无粉尘接触史者为对照组,应用SPSS 17.0对两组人群心脏超声测得的EF斜率结果进行统计分析。结果暴露组二尖瓣EF斜率[(73.20±20.53)mm/s]显著低于对照组[(78.74±24.11)mm/s](t=14.521,P<0.001),暴露组二尖瓣EF斜率降低检出率(52.4%)高于对照组(40.5%)(χ~2=22.874,P<0.001)。细颗粒物暴露是仅次于年龄、收缩压的影响二尖瓣EF斜率降低的危险因素,剔除BMI等因素后,OR值为1.744(95%CI:1.395~2.180)。结论细颗粒物暴露是二尖瓣EF斜率降低的独立危险因素。
Objective To explore the effect of fine particulate matter exposure on reducing the detection rate of EF slope of mitral valve. Methods Workers with health examination in Kailuan Group were selected during the same period. Workers with first-stage pneumoconiosis served as the exposure group,while workers without dust exposure history were considered as the control group. SPSS 17.0 software was used to statistically analyze the cardiac ultrasound results of the two groups. Results Mitral valve EF slope rate was significantly lower in the exposure group than in the control group（（ 73. 20 ± 20. 53） mm/s vs.（ 78. 74 ±24.11） mm/s,t = 14.521,P〈0.001）. The detection rate of mitral valve EF slope reduction was higher in the exposure group than in the control group（ 52.4% vs. 40.5%,χ^2= 22.874,P〈0.001）. Exposure to fine particulate matters was second only to age and systolic pressure in terms of the risk factors affecting the decrease of mitral valve EF slope,and the OR value was 1.744（ 95%CI：1.395-2.180） after the factors such as body mass index（ BMI） were excluded. Conclusion Fine particulate matter exposure is an independent risk factor for the decrease of mitral valve EF slope.
作者
周春霞
邵仲达
郑瑶
王艳
李小华
王德军
李继奎
朱秀萍
秦天榜
么太成
陈朔华
刘运秋
ZHOU Chun-xia;SHAO Zhong-da;ZHENG Yao;WANG Yan;LI Xiao-hua;WANG De-jun;LI Ji-kui;ZHU Xiu-ping;QIN Tian-bang;YAO Tai-cheng;CHEN Shuo-hua;LIU Yun-qiu(Kailuan Hospital of Occupational Disease Prevention and Treatment,Tangshan,Hebei 063301,China)
出处
《实用预防医学》
CAS
2018年第10期1172-1175,共4页
Practical Preventive Medicine
基金
河北省医学科学研究重点课题指导项目(20150830)
关键词
细颗粒物
二尖瓣EF斜率
心脏超声
尘肺病
fine particulate matter
mitral valve EF slop
cardiac ultrasound
pneumoconiosis
