摘要
杯[4]芳烃和氯乙酸乙酯在碱性条件下反应制得杯[4]芳烃四乙酸乙酯(b); b经肼解反应制得杯[4]芳烃四乙酰肼(c),再与胆固醇氯甲酸脂反应合成了以肼片段为连接臂的杯[4]芳烃四胆固醇衍生物(d),其结构经~1H NMR,IR,MS和元素分析表征。
Calix[4]arenetetraethylacetate（ b ） was synthesized by reaction of calix[4] arene with chloroacetate under alkaline condition. Then, calix[4]arenetetracethydrazide（ c ） was synthesized by reaction of b with hydrazine hydrate. Finally, calix[4]arene derivative（ d ） containing tetracholesterols was obtained through the reaction of c with cholesterol chloroformate. The structure was characterized by 1 H NMR , IR, MS and elemental analysis.
作者
蔡秀琴
CAI Xiu-qin(College of Chemistry and Environment,Weinan Normal University,Weinan 714099,China;Shaanxi Province Engineering Research Center of Coal Conversion Alcohol,Weinan 714099,China)
出处
《合成化学》
CAS
CSCD
北大核心
2018年第9期687-690,共4页
Chinese Journal of Synthetic Chemistry
基金
国家自然科学基金资助项目(21703157)
陕西省科技厅项目(2014JQ2-2008)
渭南师范学院人才项目(15ZRRC11)
关键词
杯[4]芳烃
胆固醇
肼
合成
calix[4]arene
cholesterol
hydrazine hydrate
synthesis
