期刊文献+

洛铂与顺铂同步调强放疗对Ⅱb-Ⅲb期宫颈癌临床分析 被引量:1

下载PDF
导出
摘要 目的评价洛铂与顺铂在Ⅱb-Ⅲb期宫颈癌同步调强放疗中的近期疗效和毒副反应。方法 56例初治Ⅱb-Ⅲb期宫颈癌随机分为2组,对照组28例(洛铂10mg/m^2每周同步化疗),观察组28例(顺铂30 mg/m^2每周同步化疗),比较两组近期疗效与副反应。结果洛铂组与顺铂组的有效率分别为96.43%与92.86%,两组比较差异无统计学意义(P>0.05);洛铂组的胃肠道反应低于顺铂组(39.29%vs.57.14%)(P<0.05);洛铂组与顺铂组骨髓抑制发生率分别为17.86%和14.29%,两组比较差异无统计学意义(P>0.05)。结论洛铂和顺铂同步调强放疗Ⅱb-Ⅲb期宫颈癌近期疗效无明显差异,洛铂消化道反应较低。
作者 王伟明
出处 《哈尔滨医药》 2018年第4期358-359,共2页 Harbin Medical Journal
  • 相关文献

参考文献3

二级参考文献18

  • 1黄曼妮,吴令英,高菊珍.宫颈癌的同步放化疗[J].癌症进展,2004,2(5):320-326. 被引量:60
  • 2刘少兵,周祖金,陈森,覃瑞萍.同步放化疗治疗中晚期宫颈癌[J].肿瘤防治研究,2007,34(3):204-206. 被引量:14
  • 3Whitney CW,Sause W,Bundy BN,et al.Randomized cornparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stages ⅡB-ⅣA carcinoma of the cervix with negative para-aortic lymph nodes:a Gyneco1ogic Oneology Group and Southwest Oncology Group Study[J].J Clin Oncol,1999,17(5):1339-1348. 被引量:1
  • 4Morris M,Eifel PJ,Lu J,et al.Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer[J].N Engl J Med,1999,340(15):1137-1143. 被引量:1
  • 5Keys HM,Bundy BN,Stehman FB,et al.Cisplatin,radiation,and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma[J].N Engl J Med,1999,340(15):1154-1161. 被引量:1
  • 6Peters WA 3rd,Liu PY,Barrett RJ 2nd,et al.Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix[J].J Clin Oncol,2000,18(8):1606-1613. 被引量:1
  • 7Herod J,Burton A,Buxton J,et al.A randomised,prospective,phase III clinical trial of primary bleomycin,ifosfamide and cisplatin(BIP) chemotherapy followed by radiotherapy versus radiotherapy alone in inoperable cancer of the cervix[J].Ann Oncol,2000,11(9):1175-1181. 被引量:1
  • 8Pearcey R,Brundage M,Drouin P,et al.Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix[J].J Clin Oncol,2002,20(4):966-972. 被引量:1
  • 9Yazigi R,Aliste G,Torres R,et al.Phase III randomized pilot study comparing interferon alpha-2b in combination with radiation therapy versus radiation therapy alone in patients with stage III-B carcinoma of the cervix[J].Int J Gynecol Cancer,2003,13(2):164-169. 被引量:1
  • 10Nagy V,Coza O,Ordeanu C,et al.Radiotherapy versus concurrent 5-day cisplatin and radiotherapy in locally advanced cervical carcinoma.Long-term results of a phase III randomized trial[J].Strahlenther Onkol,2009,185(3):177-183. 被引量:1

共引文献32

同被引文献6

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部