摘要
目的 分析急性脑梗死患者应用瑞舒伐他汀治疗后颈动脉粥样硬化斑块及血清超敏C反应蛋白（hs-CRP）水平变化情况.方法 选取2016年1月至2017年6月医院收治的109例急性脑梗死患者,采用随机数字表法分为两组,对照组54例给予阿托伐他汀治疗,观察组55例给予瑞舒伐他汀治疗,比较两组患者治疗后hs-CRP、血脂及颈动脉粥样硬化斑块厚度变化.结果 观察组治疗后总胆固醇（TC）、三酰甘油（TG）、低密度脂蛋白胆固醇（LDL-C）、hs-CRP水平及颈动脉粥样硬化斑块厚度均低于对照组（P均〈0.05）.结论 瑞舒伐他汀能够有效降低急性脑梗死患者炎症因子及血脂水平,逆转动脉粥样硬化斑块.
Objective To analyze the changes of carotid atherosclerotic plaque and levels of ser- um high-sensitivity C-reactive protein （hs-CRP） in patients with acute cerebral infarction treated with risuvastatin were analyzed. Methods A total of 109 patients with acute cerebral infarction treated in the hospital from January 2016 to June 2017 were divided into two groups by random digital table, 54 cases in control group were treated with atorvastatin, and 55 cases in observation group were treated with rosuvastatin. The changes of hs-CRP, blood lipid and carotid atherosclerotic plaque thickness were compared between the two groups after treatment. Results After treatment, total cholesterol （TC）, triglycerides （TG）, low-density lipoprotein （LDL-C）, hs-CRP and carotid atherosclerotic plaque thickness of the observation group were lower than those of the control group （P 〈 0. 05）. Conclusions Resuvastatin can effectively reduce inflammatory factors and blood lipid levels in patients with acute cerebral infarction and reverse atherosclerotic plaque.
出处
《中国实用医刊》
2018年第16期104-105,109,共3页
Chinese Journal of Practical Medicine
关键词
瑞舒伐他汀
急性脑梗死
超敏C反应蛋白
颈动脉粥样硬化斑块
Reshuvastatin
Acute cerebral infarction
High sensitivity C-reactive protein
Carot- id atherosclerotic plaque
