摘要
目的观察伴有椎动脉优势（VAD）的后循环梗死患者的血流动力学变化。方法将临床表现为后循环梗死、头晕和眩晕、头痛等症状共156例患者，根据头颅MRA椎动脉优势评判标准分为伴VAD组（86例）和不伴VAD组（70例），通过TCD观察每组后循环供血动脉的血流动力学变化。结果伴VAD组优势侧椎动脉Vs、Vd、vm值高于非优势侧，也高于不伴VAD组（P〈0．05）。伴VAD组基底动脉Vd和Vm值低于不伴VAD组（P〈0．05），PI和RI高于不伴VAD组（P〈0．05）。两组大脑后动脉的vs、Vd、Vm、PI、RI值比较差异均无统计学意义（P〉0．05），伴VAD组出现频谱形态异常。结论伴VAD患者出现脑血流动力学改变，优势侧椎动脉血流速度增快，基底动脉血流速度减慢，可能是造成后循环梗死的原因之一。
Objective To observed hemodynamic changes in the posterior circulation infarction patients with vertebral artery dominance （VAD）. Methods According to magnetic resonance angiography （MRA） and the diagnostic criteria of VAD, 156 patients with posterior circulation infarction （PCI）, dizziness and headache were divided into VAD group （n=86） and non-VAD group （n=70）. All enrolled subjects were performed transcranial Doppler uhrasound （TCD） examination. Results The values of systolic velocity （Vs）, mean velocity （Vm） and diastolic velocity （Vd） in the dominant VA of VAD group were higher than those in the non-dominant VA of VAD group and bilateral VA of non-VAD group （P 〈 0.05）. Compared with bosic artery of two groups, the level of Vd and Vm in the VAD group were less than those in the non-VAD group （P 〈 0.05）, and the level of pulsatility index （PI） and resistance index （RI） were higher than those in the non-VAD group （P 〈 0.05）. There were no significant difference in Vs, Vd, Vm, PI and RI of posterior cerebral artery （PCA） in two groups （P 〉 0.05）. Conclusions There are cerebral hemodynamic changes in VAD patients. The blood flow velocity of the dominant VA is faster than that of non-dominant VA, which may be due to posterior circulation infarction.
出处
《神经疾病与精神卫生》
2018年第6期423-426,F0003,共5页
Journal of Neuroscience and Mental Health
基金
苏州市科技发展计划项目（SYSD2016114）
关键词
后循环梗死
推动脉优势
血流动力学
Posterior circulation infarction
Vertebral artery dominance
Hemodynamics
