摘要
目的为了预防人工流产术后发生宫腔粘连,观察人工流产术后宫腔使用医用几丁糖联合口服屈螺酮炔雌醇片对术后宫腔粘连发生的预防效果。方法收集2015年8月~2017年10月来我院进行人工流产手术的400例患者,根据术后治疗方法的不同,分为A组(研究组)、B组(医用几丁糖组)、C组(屈螺酮炔雌醇片组)、D组(对照组),每组100例。A组宫腔内推注医用几丁糖联合口服屈螺酮炔雌醇片治疗,B组宫腔内推注医用几丁糖,C组口服屈螺酮炔雌醇片,D组术后口服抗生素和益母草颗粒,观察四组患者术后阴道出血情况、月经情况,比较四组人流术后宫腔粘连的临床效果。结果 A组月经量、阴道出血时间、首次月经复潮时间与B、C、D组相比,差异均具有统计学意义(P<0.05;A组宫腔粘连发生5例(5%)低于B13例(13%)、C18例(18%)、D25例(25%),差异均具有统计学意义(P<0.05)。结论医用几丁糖联合口服屈螺酮炔雌醇片可降低宫腔粘连发生机率,在临床上具有推广价值。
Objective： To investigate the efficacy of chitosan combined with drospirenone-ethinylestradiol tablets on prevention of intrauterine adhesion in patients after induced abortion. Methods： Totally, 400 patients undergoing induced abortion in our hospital from August 2015 to October 2017, were selected as the objects of study. They were divided into A group（test group）, B group（chitosan group）, C group（drospirenone-ethinylestradiol tablets group）, and D group（control group） with 100 patients in each group. After induced abortion, patients in A group were treated with chitosan combined with drospirenone-ethinylestradiol tablets. Patients in B group were treated with chitosan. Patients in C group were treated with drospirenone-ethinylestradiol tablets. Patients in D group were treated with antibiotics combined with leonurus granules. Postoperatively, the vaginal bleeding, menstruation, intrauterine adhesion were compared among the four groups. Results： Compared with B,C,D group, patients in A group with the menstrual flow, shorten vaginal bleeding time, earliest time of first menses. There were 5 patients with intrauterine adhesion in A group（5%）, 13 patients in B group（13%）, 18 patients in C group（18%）, and 25 patients in D group（25%）（P〈0.05）, with statistical significance. Conclusions： Chitosan combined with drospirenone-ethinylestradiol tablets can reduce intrauterine adhesion in patients after induced abortion, worth promoting.
作者
刘畅
杜巧梅
房雅
Chang Liu;Qiaomei Du;Ya Fang(53th Central Hospital of People＇s Liberation Army,Zhengzhou,Henan 850000,China)
出处
《西藏医药》
2018年第4期76-78,共3页
Tibetan Medicine
关键词
医用几丁糖
屈螺酮炔雌醇片
宫腔粘连
人工流产
Chitosan
Drospirenone-ethinylestradiol Tablets
Intrauterine Adhesion
Induced Abortion
