摘要
子宫腺肌病是影响育龄妇女生殖健康的常见疾病,其诊治尚无统一标准。越来越多的研究提示子宫腺肌病对女性生育力有负面影响,对子宫腺肌病合并不孕的患者,药物治疗和保守性手术能减轻其相关症状,增加妊娠机会,但妊娠后有子宫破裂风险。辅助生殖技术是治疗其不孕症的有效治疗措施,选择适当的降调节和促排卵方案,必要时全胚冷冻+降调后的冻融胚胎移植,可以获得满意的助孕结局。妇产科及生殖科医师应全面考虑患者的具体情况,必要时联合应用药物、手术及辅助生殖技术,为子宫腺肌病合并不孕症的患者制定个体化的助孕策略。
Adenomyosis is a common disease affecting reproductive health of women of childbearing age.There is no uniform standard of diagnosis and treatment for adenomyosis.More and more studies suggest that adenomyosis has negative impacts on female fertility and it is associated with infertility.Drug therapy and conservative surgery can alleviate the patients' symptoms and increase the chance of pregnancy,but there is a risk of uterine rupture after pregnancy.New procedures in recent years have also provided more choices for these patients.Assisted reproductive technology is effective to treat their infertility.Selecting appropriate down-regulation and ovulation induction protocol,whole embryo freezing plus down-regulation of frozen-thawed embryo transfer if necessary,can obtain satisfactory pregnancy outcome.Obstetrics and gynecology and reproductive physicians should comprehensively consider the specific condition of patients,and if necessary,combined with the application of drugs,surgery and assisted reproductive technology,to develop individualized assisted pregnancy strategies for patients with adenomyosis infertility.
作者
焦雪丹
张清学
JIAO Xue-dan;ZHANG Qing-xue(Sun Yat-sen Memorial Hospital,Sun Yat-Sen University,Guangzhou 510000)
出处
《生殖医学杂志》
CAS
2018年第9期888-891,共4页
Journal of Reproductive Medicine
基金
逸仙临床研究培育项目
关键词
子宫腺肌病
不孕症
手术治疗
辅助生殖技术
Adenomyosis
Infertility
Surgical treatment
Assisted reproductive technology