摘要
目的探讨内镜光动力微创技术治疗胆管癌的临床效果。方法选取2015年1月~2017年6月我院收治的120例胆囊癌患者作为研究对象。按照随机数字表法将患者分为研究组(60例)和对照组(60例)。对照组患者采用内镜下支架置入术,研究组患者在此基础之上采用光动力疗法。比较两组患者不同时期的生活质量(QOL)评分。结果在生活质量的评分量表中,研究组中患者术后3、6、9、12个月的生理情况、社会/家庭情况、情感情况、肝胆肿瘤的特异性的症状评分和总QOL评分均明显高于术前,差异有统计学意义(P<0.05);而对照组中,仅有术后3、6个月的生理情况、社会/家庭情况、情感情况、肝胆肿瘤的特异性的症状评分和总QOL评分明显高于术前,差异有统计学意义(P<0.05);两组手术前的总QOL评分比较,差异无统计学意义(P>0.05);两组术后6、9、12个月的总QOL评分比较,差异有统计学意义(P<0.05);研究组患者的总有效率显著高于对照组,差异有统计学意义(P<0.05);研究组的不良反应总发生率显著低于对照组,差异有统计学意义(P<0.05)。结论内镜下光动力微创疗法能够显著提高患者的生活质量,治疗效果显著,不良反应发生率低,值得在临床上广泛推广。
Objective To investigate the clinical efficacy of endoscopic photodynamic minimally invasive techniques in the treatment of cholangiocarcinoma. Methods A total of 120 patients with gallbladder cancer who were admitted to our hospital from January 2015 to June 2017 were selected as the study subjects. The patients were randomly divided into study group（60 cases） and control group（60 cases） according to the random number table method. The patients in the control group were given endoscopic stenting. The patients in the study group were given photodynamic therapy on this basis. The quality of life（QOL） scores were compared between the two groups at different times. Results In the scale of quality of life, the physical conditions, social/family conditions, emotional conditions, hepatobiliary tumor-specific symptoms and total QOL scores at 3, 6, 9 and 12 months postoperatively in the study group were all significantly higher than those before the surgery, and the differences were statistically significant（P〈0.05）. In the control group, only the physical conditions, social/family conditions, emotional conditions, hepatobiliary tumor-specific symptoms, and total QOL scores at 3 and 6 months after surgery were significantly higher than those before surgery, and the differences were statistically significant（P〈0.05）. The total QOL scores before surgery were compared between the two groups, and the difference was not statistically significant（P〈0.05）. The differences of the total QOL scores in the two groups at 6,9 and 12 months after surgery were statistically significant（P〈0.05）. The total effective rate in the study group was significantly higher than that in the control group, and the difference was statistically significant（P〈0.05）. The overall incidence rate in the study group was significantly lower than that in the control group, and the difference was statistically significant（P〈0.05）. Conclusion Endoscopic photodynamic minimally invasive therapy can significantly im
作者
邓平
DENG Ping(Department of General Surgery,People＇s Hospital of Cili County,Hu＇nan Province,Cili 427200,China)
出处
《中国当代医药》
2018年第23期112-114,117,共4页
China Modern Medicine
关键词
胆管癌
内镜下光动力
微创技术
治疗效果
Cholangiocarcinoma
Endoscopic photodynamic therapy
Minimally invasive technique
Therapeutic effect
