摘要
目的：观察电针干预内关、关元、足三里穴对动脉粥样硬化家兔血脂及血液流变学相关指标的影响。方法：采用高脂饲养＋颈总动脉球囊损伤术法建立动脉粥样硬化（AS）模型。实验设正常组、模型组、针刺组、阳性药物对照组。治疗结束后,取兔血液,检测血脂及血液流变学相关指标。结果：针刺能降低AS模型家兔血清甘油三酯、胆固醇、低密度脂蛋白含量（P〈0.01）,升高高密度脂蛋白含量（P〈0.01）,针刺组家兔全血黏度（低切、中切、高切）,毛细管血浆黏度,全血还原黏度（低切、中切、高切）,红细胞聚集指数,红细胞压积明显低于模型组（P〈0.01）。结论：针刺可改善动脉粥样硬化模型家兔血脂及血液流变学相关指标,对动脉粥样硬化具有防治作用。
Objective：To observe the effect of electroacupuncture at Neiguan（ PC6）,Guanyuan（ RN4） and Zusanli（ ST36） on the blood lipid and hemorheology indexes of atherosclerotic rabbits. Methods：AS model was established by high fat feeding and common carotid artery balloon injury. The experimental group was divided into normal group,model group,acupuncture group,positive drug control group. At the end of treatment,the rabbit blood was taken out to detect the indexes of blood lipid and hemorheology. Results：Acupuncture can decrease serum TG,CHO and LDL-C contents of the AS models（ P〈0. 01）,increase the content of HDL-C（ P〈0. 01）,the whole blood viscosity（ low,middle and high shear） and capillary plasma viscosity,reduce blood viscosity（ low,middle and high cut） and erythrocyte cell aggregation index and hematocrit of acupuncture group were significantly lower than those of the model group（ P〈0. 01）. Conclusion：Acupuncture can improve the indexes of blood lipid and hemorheology in rabbits with atherosclerosis,and can prevent atherosclerosis.
作者
栾海燕
成泽东
LUAN Haiyan;CHENG Zedong(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)
出处
《辽宁中医杂志》
CAS
2018年第8期1761-1763,I0002,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金项目(81673956)
关键词
电针
动脉粥样硬化
血脂
血液流变学
electroacupuncture
atherosclerosis
blood lipid
hemorheology
