摘要
目的:对广东省深圳市南山区西丽人民医院注射用血塞通(冻干)应用情况及不良反应进行分析,为该药安全合理使用提供参考。方法:采用医院集中监测的方法,对广东省深圳市南山区西丽人民医院2015年11月~2016年10月期间使用注射用血塞通(冻干)的门诊及住院患者进行集中登记监测,并进行统计。结果:共监测应用此药物患者237例,其中女性患者84例,男性患者153例。40~60岁患者的比例最大(占比51.1%),使用基本符合药品说明书规定。不良反应发生率为4.64%,均表现为皮肤及附件的损害如皮疹、瘙痒等,无明显特异性,所有药物不良反应(adverse drug reaction,ADR)经停药或对症处理后均好转。结论:医院集中检测法是对自发性呈报系统良好的补充,其得出的不良反应发生率具有可参考性,但需要进行多中心的研究,使数据更具代表性。
Objective： To analyze the clinical application and adverse reaction of Xue Sai Tong Injections in our hospital,and to provide reference for safe and rational use of it.Methods： By the method of hospital intensive monitoring,the outpatient and inpatient from November 2015 to October 2016 in our hospital were central monitored, and statistically analyzed the ADR of Xue Sai Tong Injections.Results： We collected 237 cases including 84 females and 153 males. The largest group is 40 to 60 years old. In most cases, indications and drug use are consistent with the drug instruction. The incidence of ADR is 4.64%.All adverse reactions were manifested as skin and adnexal lesions, such as skin rashes and itching, without obvious specificity, and improved after drug withdrawal or symptomatic treatment. Conclusion： Hospital intensive monitoring method is a good supplement of spontaneous reporting system, which can get a referential incidence rate of ADR, but multicenter studies are needed to make the data more representative.
作者
钱万桥
QIAN Wan-qiao(Department of Pharmacy,Xili Peoples Hospital,Shenzhen Guangdong 518055,China)
出处
《药品评价》
CAS
2018年第17期54-57,64,共5页
Drug Evaluation
基金
广东省深圳市南山区技术研发和创意设计项目分项资金教育(卫生)科技资助项目
注射用血塞通(冻干)安全性医院集中监测(项目编号2015062)
关键词
注射用血塞通(冻干)
不良反应
合理用药
医院集中监测
Xue Sai Tong Injections
Adverse Reaction
Rational Drug Use
Hospital Intensive Monitoring
