摘要
在三氟甲基磺酸铜的催化下,以氧气为氧化剂,取代苯胺、乙醛酸乙酯、简单烯烃可顺利发生三组份串联氧化反应,以较高的收率得到具有一定抗原虫活性的取代喹啉衍生物,该体系的唯一副产物是无污染的水分子,为喹啉的合成提供了一种绿色环保的新方法.
Under the catalysis of copper trifluoromethanesulfonate, the substitution of aniline, ethyl glyoxylate and simple olefin with oxygen as oxidant can smoothly undergo a thine - component series oxidation reaction, and a substituted quinoline derivative having certain antigenic insect activity can be obtained in a high yield. The only by - product of the system is Non - polluting water molecules provide a new given environmental protection method for the synthesis of quinoline.
作者
谢智宇
司路路
蒋莉伟
刘雨晴
XIE Zhiyu;SI Lulu;JIANG Liwei;LIU Yuqing(College of Chemistry and Chemical Engineering,Xuchang University,Xuchang 461000,China)
出处
《许昌学院学报》
CAS
2018年第8期38-41,共4页
Journal of Xuchang University
基金
河南省2018重点研发与推广专项科技公关项目(182102310066)
河南省教育厅重点项目(18B35007)
许昌市科技局基础研究项目(201703)
关键词
多组分反应
氧气
铜盐
喹啉
muhi - component reaction
oxygen
copper salt
quinioline
