摘要
抑郁症患者通常自我报告时间感知变慢,但是抑郁水平如何影响其时间知觉的问题并未得到解决.本研究通过行为实验及事件相关电位技术,采用时间等分任务范式,考察临床抑郁症患者和阈下抑郁个体在400~1600 ms范围内时间知觉的行为特点与可能的机制.结果发现:(1)临床和阈下抑郁症组的韦伯比例均高于对照组,主观等分点与对照组无差异,临床和阈下抑郁组均表现出"长时距高估,短时距低估"的趋势.(2)阈下抑郁组的韦伯比例与其抑郁程度正相关,但主观等分点与其状态抑郁和特质抑郁均不相关.(3)阈下抑郁组的P2波幅呈下降趋势,CNV潜伏期延迟,且在400 ms时距上,LPCt的波幅降低,但N1波幅与对照组无差异.上述结果提示,阈下抑郁组与临床抑郁症组的时间知觉表现出类似的改变,并且随着抑郁程度的加深,被试在时间加工中表现出了更多的变异.阈下抑郁个体时间知觉的改变,可能与内部时钟阶段无足够的认知资源参与时间加工有关.此外,阈下抑郁组CNV峰值潜伏期延迟,其后伴随的正向偏转LPCt波幅减小,反应时变慢,提示阈下抑郁组在决策阶段也表现出一定的改变.
Time perception is the basis of cognitive processing, and it may be affected by depression levels. People with depression often report slower subjective time experience; however, whether depression levels affect time perception has not been determined. More than 300 million people of all ages suffer from depression globally, and this number might be much larger if people with subthreshold depression, which indicates that an individual has clinically relevant depressive symptoms without meeting the criteria for full-blown major depressive disorder, are included. In this study, we examined the behavioral characteristics of time perception in patients with clinical depression and individuals with subthreshold depression based on a temporal bisection within the range of 400–1600 ms. The data were then fitted to a sigmoidal curve in order to calculate the subjective bisection point and Weber ratios. In addition, the event-related potential（ERP） responses of time perception in individuals with subthreshold depression were recorded to explore the possible mechanisms. The results were as follows：（1） The Weber ratios of individuals in the clinical and subthreshold depression groups were higher than those in the control group. There was no significant difference in the subjective bisection point between either the subthreshold depression group or the clinical depression group and the control group. Both the clinical and subthreshold depression groups had longer reaction times in each duration, and they tended to overestimate short durations and underestimate long durations.（2） The levels of depression（both trait depression and state depression） were positively related to the Weber ratio, and there was no correlation between the bisection point and either trait depression or state depression.（3） The P2 amplitude of the subthreshold depression group showed a decreasing trend, and the latency of the contingent negative variation（CNV） was delayed. The amplitude of the late positive component of timi
作者
陶丹
李朋
宣宾
周晶
李明珠
Dan Tao;Peng Li;Bin Xuan;Jing Zhou;Mingzhu Li(School of Educational Science,Anhui Normal University,Wuhu 241000,China;School of Liberal Arts,Anhui Normal University,Wuhu 241000,China)
出处
《科学通报》
EI
CAS
CSCD
北大核心
2018年第20期2036-2047,共12页
Chinese Science Bulletin
基金
国家自然科学基金(31171076)资助
关键词
临床抑郁症
阈下抑郁
时间知觉
事件相关电位
clinical depression
subthreshold depression
time perception
event-related potentials
