摘要
目的探讨分析中药序贯周期治疗卵巢储备下降的临床疗效。方法选取2016年1月—2018年1月本院妇产科收治的118例卵巢储备功能下降患者随机分为观察组和对照组,观察组患者给予中药序贯周期治疗,对照组患者给予西药治疗,比较两组患者临床疗效,治疗前后FSH、E2、LH、AMH指标水平、临床体征评分。结果观察组患者临床疗效显著提高,总有效率为93.22%,差异具有统计学意义(P<0.05)。治疗前两组患者FSH、E2、LH、AMH指标水平、临床体征评分差异无统计学意义(P>0.05),治疗后两组患者FSH、LH指标水平下降,E2、AMH指标水平上升,且观察组患者FSH、E2、LH、AMH指标水平改善效果更好,烘热汗出、烦躁易怒、健忘失眠、头晕耳鸣、腰膝酸软评分较对照组显著下降,差异均具有统计学意义(P<0.05)。结论中药序贯周期治疗卵巢储备功能下降可显著提高临床疗效,改善FSH、E2、LH、AMH指标水平和临床症状,且安全性较高,值得推广。
Objective： To investigate the clinical curative effect of traditional Chinese medicine sequential cycles on the decline of ovarian reserve. Methods： 118 patients with decreased ovarian reserve in the Department of Obstetrics and Gynecology from January 2016 to January 2018 were selected and divided into the observation group and the control group randomly. The patients in the observation group were given the sequential treatment of traditional Chinese medicine,and the patients in the control group were given the western medicine treatment. Te clinical efficacy between the two groups,and the levels of FSH,E2,LH,AMH,and clinical signs before and after treatment were compared. Results： The clinical efficacy of the observation group was significantly improved,the total effective rate was 93. 22%,the difference was statistically significant（P〈0. 05）. There was no significant difference in the levels of FSH,E2,LH,AMH,and clinical signs between the two groups before treatment.（P〉0. 05） After treatment,the levels of FSH,E2,and LH,sweating,irritability,forgetfulness,insomnia,dizziness,tinnitus,and tenderness of the waist and knees were significantly decreased,and the AMH index was significantly elevated in the observation group. The levels of FSH,E2,LH and AMH improved more significantly in patients,and the differences were statistically significant（P〈0. 05）. Conclusion： The sequential cycle of traditional Chinese medicine treatment of ovarian reserve can significantly improve the clinical efficacy,improve the level of FSH,E2,LH,AMH indicators and clinical symptoms,and safety,and it is recommended in the clinical promotion.
作者
刘凯娅
覃秋萍
LIU Kai-ya ,QIN Qiu-ping(Dept. of Gynaecology, Guangzhou Municipal Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou 510800, China)
出处
《泰山医学院学报》
CAS
2018年第7期756-759,共4页
Journal of Taishan Medical College
基金
广州市花都区科技计划项目(16-HDWS-010)
关键词
中药序贯周期治疗
卵巢储备
临床疗效
traditional Chinese medicine sequential cycle treatment
ovarian reserve lelinieal efficacy
