摘要
目的探讨宫腔镜手术后联合大剂量戊酸雌二醇(E2V)周期疗法治疗重度宫腔粘连的可行性。方法回顾性分析62例重度宫腔粘连患者,宫腔镜下行宫腔粘连电切术+上环术后立即使用大剂量E2V周期疗法(观察1组)、小剂量E2V周期疗法(观察2组)和未正规使用激素治疗(对照组)的3组患者的临床资料,分析疾病预后。结果观察1组及观察2组月经恢复的总有效率高于对照组,差异有统计学意义(P<0.05);观察1组高于观察2组(P<0.05)。观察1组宫腔恢复的总有效率高于观察2组及对照组,差异均有统计学意义(P<0.05);观察1组的疗效高于观察2组(P<0.05)。观察1组子宫内膜的厚度高于观察2组及对照组,差异均有统计学意义(P<0.05)。结论宫腔镜术后联合大剂量E2V周期疗法可显著提高重度宫腔粘连的疗效,是一种安全、可靠的治疗方法。
Objective To explore the possibility of periodic treatment of high dose asteroidal valerate（E2 V） after hysteroscopy surgery on serious intrauterine adhesion. Methods The post-operative effects of periodic high-dose E2 V treatment was compared with retrospective analysis on 62 cases of serious intrauterine adhesion and their clinical files. The cases were divided to 3 groups： immediate high-dose periodic treatment of E2 V after hysteroscopy electric resection ＋ contraceptive ring fitting（ experiment group I）,low-dose periodic treatment of E2 V（ experiment group II）,and Irregular use of hormone treatment（ control group）. Results The effective rate of menstruation recovery of experiment group I and that of experiment group II are higher than control group（ P〈0. 05）;experiment group I is higher than experiment group II（ P〈0. 05）. The effective rate of Intrauterine recovery of experiment group I is higher than experiment group II and control group（P〈0. 05）; the curative effect of experiment group I is higher than experiment group II（P〈0. 05）. The endometrium of experiment group I is thicker than experiment group II and control group（ P〈0. 05）. Conclusion The use of high dose asteroidal valerate after hysteroscopy surgery on serious intrauterine adhesion,which improves the treatment effectively,is reliable and safe.
作者
任旭
付霞霏
REN Xu;FU Xiafei(Nanhai hospital of southern medical university,Foshan 528200,China)
出处
《现代医院》
2018年第5期728-730,733,共4页
Modern Hospitals
基金
广东省科技厅科技计划项目(20140212)
广东省中医药局面上项目(20171207)
广州市医药卫生科技项目(2013A011030016)
关键词
宫腔粘连
戊酸雌二醇
宫腔镜下宫腔粘连分离术
Intrauterine Adhesion
Asteroidal Valerate
Transcervical Resection of Adhesions（TCRA）
