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右美托咪定复合瑞芬太尼在胃镜检查中的应用 被引量:4

Application of dexmetomidine with remifentanil to gastroscopy
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摘要 目的观察右美托咪定复合瑞芬太尼用于胃镜检查中的麻醉效果。方法将拟行胃镜检查对象90例,按随机数字表法分为A组、B组,A组采用右美托咪定+瑞芬太尼复合麻醉;B组采用右美托咪定+舒芬太尼复合麻醉。观察患者的生命体征在检查过程中各时间节点的变化情况、不良反应发生率、入睡时间、苏醒时间、总滞留时间以及相关满意度。结果 A组患者的生命体征变化在胃镜检查过程中显著低于B组(P<0.05);不良反应发生率低于B组(15.6%比48.9%,χ2=11.447,P<0.05);两组患者入睡时间、苏醒时间在麻醉给药后,A组显著低于B组(P<0.05);但两组患者的镜检时间、总滞留时间差异无统计学意义(P>0.05);A组患者满意度明显高于B组(P<0.05)。结论右美托咪定复合瑞芬太尼用于无痛胃镜检查,患者生命体征更趋稳定、不良反应发生率较低、苏醒时间较短、患者满意度较高。 Objective To observe the anesthetic effects of dexmetomidine combined with remifentanil in painless gastroscopy. Methods Ninty patients with painless gastroscopy were randomized into group A and B. Patients in group A were given dexmetomidine and remifentanil,and the group B were given dexmetomidine and sufentanil. The pertaining to the changes of vital signs in the examination,the incidence of adverse reactions,time of falling asleep,waking up and leaving hospital as well as patients’ satisfaction were observed in two groups of patient. Results The changes of vital signs and incidence of adverse reactions of group A were obvious lower than those of group B. The fall asleep upon anesthesia and earlier wake-up after examination of group A were obvious shorter than group B( all P 〈 0. 05). The two groups were no significant between two group in the time of examination and the time to leave hospital( P 〉 0. 05). Patients’ satisfaction rates of group A were higher than group B( P 〈 0. 05). Conclusion Dexmetomidine combined with remifentanil can maintain stable vital signs,reduce the adverse reactions,shorten the wake-up and improve the satisfaction of patients.
作者 路强 丁路 郭玲玲 李同海 韩正飞 Lu Qiang,Ding Lu,Guo Lingling,Li Tonghai,Han Zhengfei(Department of Anesthesiology,Fuyang Hospital of Traditional Chinaese Medicine, Fuyang 236025, China)
出处 《中国临床保健杂志》 CAS 2018年第4期518-520,共3页 Chinese Journal of Clinical Healthcare
关键词 麻醉 静脉 胃镜检查 右美托咪定 瑞芬太尼 病人满意度 Anesthesia,intravenous Gastroscopy Dexmedetomidine Remifentanil Patient satisfaction
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