摘要
目的建立慢性胃炎中医证候要素辨证量表。方法制订慢性胃炎中医症状条目池,收集2013年1月~2016年12月北京中医药大学东方医院243例慢性胃炎门诊患者的四诊资料,保留出现率≥5%的症状,基于复杂系统熵聚堆方法提取证候要素,使用统计软件SPSS 20.0,利用向前步进(条件)回归法进行条目筛选,形成条目池;运用二分类Logistic回归分析确定各症状权重系数,再利用受试者工作特征(ROC)曲线确定各证候要素的诊断阈值。结果经条目筛选最后保留有效条目共36条,在此基础上建立了慢性胃炎中医证候要素辨证量表。量表中共有气滞、气虚、热、湿、阴虚、阳虚、血瘀、寒和痰9个证候要素,60分为诊断阈值。结论慢性胃炎证候要素辨证量表的研制是对慢性胃炎证候标准化规范化进行的有益探索。
Objective To establish a TCM syndrome elements identification scale for chronic gastritis. Methods The item pool of TCM symptoms for chronic gastritis was made. The four diagnostic data of 243 outpatients with chronic gastritis in Dongfang Hospital Affiliated to Beijing University of Chinese Medicine from January 2013 to December2016 was collected, of which, TCM syndrome elements having over 5% occurrence frequency were retained. TCM syndrome elements were extracted based on complex system entropy cluster. Statistical software SPSS 20.0 was used to analyze the data, and logistic regression of forward（conditional） method was used for the selection of scale items, so as to form item pool. Binary logistic regression analysis was used to confirm the weight coefficient of all symptoms, then receiver operating characteristic（ROC） curve was used to confirm the diagnostic threshold of all syndrome elements. Results Through items screening, a total of 36 significant items were retained, on basis of which, the TCM syndrome elements identification scale for chronic gastritis was established. There were 9 syndrome elements in the scale, including qi-stagnation, qi-deficiency, fire-heat, dampness, yin-deficiency, yang-deficiency, blood stasis, cold and phlegm. The diagnostic threshold score was 60 points. Conclusion The development of TCM syndrome elements identification scale for syndrome factors of chronic gastritis is an effective exploration for standardization of chronic gastritis syndrome.
作者
郑思思
李军祥
王允亮
文占权
王丽
韩爱庆
ZHENG Sisi;LI Junxiang;WANG Yunliang;WEN Zhanquan;WANG Li;HAN Aiqing(Department of Encephalopathy,the Third Affiliated Hospital of Beijing University of Chinese Medicine,Beijing100029,China;Department of Gastroenterology,Dongfang Hospital Affiliated to Beijing University of ChineseMedicine,Beijing 100079,China;School of Administration,Beijing University of Chinese Medicine,Beijing100029,China)
出处
《中国医药导报》
CAS
2018年第18期120-123,共4页
China Medical Herald
基金
国家自然科学基金资助项目(81503407)
北京中医药大学基本科研业务费项目(2016-JYB-JSMS-019
2016-JYB-JSMS-020)
关键词
慢性胃炎
证候要素
辨证量表
标准化
Chronic gastritis
Syndrome elements
Identification scale
Standardization
