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氨氯地平阿托伐他汀钙片治疗高血压合并冠心病临床研究 被引量:5

Clinical Study on Amlodipine Besylate and Atorvastatin Calcium Tablets in the Treatment of Hypertension and Coronary Heart Disease
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摘要 目的观察氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床效果。方法选取2016年1月—2017年10月来院就诊的120例高血压合并冠心病患者,将其分为研究组和对照组。研究组服用氨氯地平阿托伐他汀钙片,对照组服用阿托伐他汀钙片,对两组临床治疗效果及并发症发生情况进行比较。结果研究组与对照组治疗总有效率分别为93.33%、66.67%,并发症发生率分别为3.33%、26.67%(P<0.05)。结论氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的效果优于阿托伐他汀钙片,安全可靠。 Objective To observe the clinical effect of amlodipine besylate and atorvastatin calcium tablets in the treatment of hypertension and coronary heart disease. Methods 120 patients with hypertension and coronary heart disease who came to hospital from January 2016 to October 2017 were selected and divided into the study group and the control group. The study group was treated with amlodipine besylate and atorvastatin calcium tablets and the control group was treated with atorvastatin calcium tablets. The clinical effects and complications of the two groups were compared. Results The total effective rate of treatment in the study group and the control group was 93.33% and 66.67% respectively, and the incidence of complications was 3.33% and 26.67% respectively(P〈0.05). Conclusion The effect of amlodipine besylate and atorvastatin calcium tablets in the treatment of hypertension and coronary heart disease is better than atorvastatin calcium tablets, it is safe and reliable.
作者 王学东 WANG Xuedong(Department of Internal Medicine,Seashore Hospital of Shengli Petroleum Administration,Dongying Shandong 257000,China)
出处 《中国卫生标准管理》 2018年第13期83-84,共2页 China Health Standard Management
关键词 氨氯地平 阿托伐他汀钙 高血压 冠心病 老年病 对照研究 amlodipine besylate atorvastatin calcium hypertension coronary heart disease geriatric disease control study
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  • 1侯旭红,王新武.应用氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的临床疗效观察[J].当代医药论丛,2014,12(1):154-155. 被引量:106
  • 2张健,姚洪森,贺南方,张辉.对老年冠心病合并高脂血症患者不同剂量阿托伐他汀治疗的临床研究[J].武警医学,2006,17(2):103-105. 被引量:8
  • 3Satoh M, Takahashi Y, Tabuchi T, et al. Cellular and mo- lecular mechanisms of statins: an update on pleiotropiceffects[J]. Clin Sci (Lond), 2015, 129 (2): 93-105. 被引量:1
  • 4Bertocchi C, Traunwieser M, Dorler J, et al. Atorvastatin inhibits functional expression of proatherogenic TLR2 in ar- terial endothelial cells [ J ]. Cell Physiol Biochem, 2011, 28 (4): 625-630. 被引量:1
  • 5Fang D, Yang S, Quan W, et al. Atorvastatin suppresses Toll-like receptor 4 expression and NF-kappaB activation in rabbit atherosclerotic plaques[ J]- Eur Rev Med Pharmacol Sci, 2014, 18 (2): 242-246. 被引量:1
  • 6Liu M, Tang R, Jiang Y. Study on the function and mecha- nism of atorvastatin in regulating leukemic cell apoptosis by the PI3K/Akt pathway[J]. Int J Clin Exp Med, 2015, 8 (3) : 3 371-380. 被引量:1
  • 7Li X, Deroide N, Mallat Z. The role of the inflammasome in cardiovascular diseases[J]. J Mol Med (Bed), 2014, 92 (4): 307-319. 被引量:1
  • 8Satoh M, Tabuchi T, Itoh T, et al. NLRP3 inflammasome activation in coronary artery disease : results from prospective and randomized study of treatment with atorvas- tatin or rosuvastatin [ J ]. Clin Sei ( Lond ), 2014, 126 (3) : 233-241. 被引量:1
  • 9Li X, Deroide N, Mallat Z. The role of the inflammasome in eardiovascular diseases [ J ]. J Mol Med ( Berl), 2014, 92 (4): 307-319. 被引量:1
  • 10Cai S, Batra S, Wakamatsu N, et al. NLRC4 inflarmnasome- mediated production of IL-lbeta modulates mucosal immtmity in the lung against gram-negative bacterial infection[J]. J Im- munol, 2012, 188 (11):5 623-635. 被引量:1

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