摘要
目的比较不同发育时期(D5和D6)冻融囊胚移植后的临床结局,为选择冷冻囊胚的最佳时期提供理论指导。方法回顾性分析2015年1月-2016年12月407例冻融囊胚移植患者临床资料。按照冷冻前形成囊胚的时间D5或D6进行分组,分为D5组和D6组,比较两组的基础临床资料、周期特征以及临床妊娠率、胚胎种植率等妊娠结局。结果 D6组的临床妊娠率和胚胎种植率均高于D5组(P<0.05);D5组和D6组患者周期特征、流产率、多胎妊娠率和异位妊娠率等方面均无统计学差异(P>0.05)。结论本中心的培养体系中冻融D6囊胚移植能获得更好的妊娠结局。
Objective To compare the pregnancy outcome of transferred blastocysts with different developmental stages in frozen-thawed cycles of in vitro fertilization-embryo transfer （IVF-ET）. Methods A retrospective analysis of 407 cases blastocyst transfer patients was performed. According to the blastocyst stage of development, they were divided into D5 group and D6 group, and indicators in two groups, including clinical pregnancy, implantation rate, pregnancy outcomes and status of patients were compared. Results D6 group in frozen-thawed cycle had a higher clinical pregnancy rate and implantation rate were significantly higher than those in D5 group （P 〈0.05）. There was no significant difference between the two groups in others characteristics （P 〉0.05）. Conclusion Frozen-thawed D6 blastocyst can result in the better pregnancy outcome in the department.
作者
赵静
胡泊
王鹏
王致辉
朱玥洁
巩晓芸
ZHAO Jing;HU Bo;WANG Peng;WANG Zhihui;ZHU Yuejie;GONG Xiaoyun(Reproduction Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,Chin)
出处
《新疆医科大学学报》
CAS
2018年第8期960-963,共4页
Journal of Xinjiang Medical University
基金
新疆维吾尔自治区自然科学基金(2017D01C284)
关键词
冻融胚胎移植
囊胚
囊胚扩张
妊娠结局
thawed
blastocyst
blastocyst expansion
pregnancy outcome
