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多发与单发乙肝相关肝细胞癌根治术后的复发率及总生存率 被引量:1

Analysis of Recurrence Rate and Overall Survival Rate of Multiple-Nodular and Single-Nodular Hepatitis B Virus-Related Hepatocellular Carcinoma after Radical Resection
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摘要 目的:探讨多发与单发乙肝相关肝细胞癌根治术后的复发率和总生存率。方法:回顾性分析28例乙肝相关肝细胞癌患者的随访资料,多发瘤患者15例(多发瘤组)和单发瘤患者13例(单发瘤组),所有患者均已行肝癌根治术,术后平均随访时间为18.1个月,术后每3个月随访1次,比较2组患者根治术后随访期内的复发率与总生存率。结果:单发瘤组患者术后复发率低于多发瘤组患者,总生存率高于多发瘤组患者,差异有统计学意义(P<0.05)。结论:单发乙肝相关性肝细胞癌患者根治术后预后优于多发肿瘤患者。 Objective: To investigate the overall survival( OS) and time to recurrence( TTR) between multiple-nodular and single-nodular Hepatitis B virus( HBV)-related hepatocellular carcinoma( HCC) after radical resection. Methods: Retrospective analysis on follow up record of 28 HBV-related HCC patients. All patients received radical resection as the treatment of HCC. 15 were multiplenodular HCC patients( multiple-nodular group),13 were single-nodular HCC patients( single-nodular group). Average follow up time is 18. 1 months after surgery,once in every three months. Overall survival rate and time to recurrence rate were analyzed between both groups. Results: The TTR of singlenodular group was lower than that of multiple-nodular group,while OS was higher than that of multiplenodular HCC group,differences were statistically significant( P〈0. 05). Conclusion: The prognosis after radical resection of single-nodular HCC patients was better than that of multiple-nodular HCC patients.
作者 朱海涛 刘哲豪 ZHU Haitao;LIU Zhehao(Department of Hepatobiliary Surgery,Affiliated Hospital of Guizhou Medical University,Guiyang 550004,Guizhou,China)
出处 《贵州医科大学学报》 CAS 2018年第7期816-818,823,共4页 Journal of Guizhou Medical University
基金 贵州省科技计划项目[黔科合LH字(2016)7232号]
关键词 肝细胞 肝炎 乙型 随访研究 肝癌根治术 复发率 生存率 carcinoma hepatocellular hepatitis B-virus Follow up study radical resection of liver cancer recurrence rate survival rate
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