摘要
目的探讨右美托咪定联合瑞芬太尼对ICU患者镇静镇痛作用的效果。方法选择ICU术后患者60例,按术后镇痛用药不同分为A、B组各30例。A组术后给予瑞芬太尼。B组术后给予右美托咪定联合瑞芬太尼。比较2组患者术后镇静镇痛效果及不良反应。结果 B组术后6、12、24 h镇静镇痛评分显著低于A组(P<0.01)。B组患者不良反应发生率为16.7%,显著低于A组的60.0%(P<0.05)。结论 ICU患者术后应用右美托咪定联合瑞芬太尼联合疗法镇静镇痛作用效果确切、可靠、安全。
Objective To study effect of dexmedetomidine combined with rufentanil on sedation and analgesia in treatment of ICU patients. Methods A total of 60 patients in ICU were selected and divided into groups A and B,with 30 cases in each group. Group A was given remifentanil,while group B was given dexmedetomidine. The sedative efficacy and adverse reactions in two groups were compared. Results The scores of sedation and analgesia at 6,12,and 24 h after operation in group B were significantly lower than that in group A（ P 〈0. 01）. The incidence rate of adverse reactions in group B was lower than that in group A（ 16. 7% vs. 60. 0%,P〈0. 05）. Conclusion The effect of dexmedetomidine combined with remifentanil has better postoperative sedation and analgesia efficacy for ICU patients,and the combined therapy is reliable,safe and worthy of clinical application.
作者
孙俊
佟春廷
殷志春
SUN Jun;TONG Chunting;YIN Zhichun(Department of Pharmacy;Department of Anesthesia;Department of ICU,County People＇s Hospital,Jinhu,Jiangsu,211600)
出处
《实用临床医药杂志》
CAS
2018年第13期104-105,108,共3页
Journal of Clinical Medicine in Practice
关键词
瑞芬太尼
右美托咪定
镇静
镇痛
rufentanil
dexmedetomidine
sedation
analgesia
