摘要
目的探讨急性渗出性放射性鼻炎鼻内镜干预最佳时机及频率。方法将广东省农垦中心医院耳鼻喉科收治的200例急性渗出性放射性鼻炎患者按入组先后顺序分为A_1、A_2、A_3、A_4、A_5共5组,每组各40例。5组患者均给予生理盐水清洗鼻道,每侧鼻腔生理用水量为300 ml,每日2次;A_1组每周实施1次鼻内镜治疗,A_2组每2周1次,A_3组每4周1次,A_4组放疗后3~6个月开始,每2周1次,A_5组仅采用生理盐水冲洗鼻道。结果入组3个月及6个月A_1、A_2组的主观感觉评分显著低于A_5组,A_1组的主观感觉评分显著低于A_3及A_4组,差异有统计学意义(P<0.05);入组1年A_1、A_2组的主观感觉评分显著低于A_3、A_4、A_5组;A_1组的主观感觉评分显著低于A_2组,差异有统计学意义(P<0.05);入组3个月后A_1组的鼻腔粘连及后鼻孔缩窄率显著低于A_5组,差异有统计学意义(P<0.05);入组6个月后,A_1组、A_2组的鼻腔粘连率显著低于A_5组,A_1组、A_2组、A_3组的后鼻孔缩窄率显著低于A_5组,A_1组的后鼻孔缩窄率显著低于A_4组,差异有统计学意义(P<0.05);入组1年A_1组的鼻腔粘连及后鼻孔缩窄率显著低于A_5、A_4组;A_1组的鼻腔粘连率显著低于A_3组,差异有统计学意义(P<0.05)。入组3个月、6个月及1年后鼻腔粘连及后鼻孔缩窄率A_1组最低,A_5组最高。结论鼻内镜治疗鼻咽癌放射后急性渗出性放射性鼻炎疗效理想,可减少脓涕分泌,改善鼻腔通气程度,缓解头痛症状,改善鼻腔粘连、后鼻孔缩窄,1年随访期内急性渗出性放射性发病后每周1次频率的鼻内镜治疗疗效最佳。
Objective To investigate the optimal timing and frequency of nasal endoscopic intervention for acute exudative radiosurgery. Methods 200 cases of acute exudative radioactive rhinitis were divided into A1 group,A2,A3,A4 and A5 group,40 cases in each group,and 5 patients were given normal saline Wash the nasal passages,each side of the nasal physiological water consumption of 300 ml,2 times a day,A1 group a week endoscopic treatment,A2 group every 2 weeks 1,A3 group every 4 weeks 1,A4 group after radiotherapy 3-6 months,once every 2 weeks,A5 group only use saline to wash the nose. Results The subjective sensory score of A1 and A2 group was significantly lower than that of A5 group at 3 months and 6 months. The subjective sensory score of group A1 was significantly lower than that of A3 and A4 group（ P〈0. 05）. The subjective sensory score of group A1 was significantly lower than that of group A2,P〈0. 05; the rate of nasal adhesions and posterior nostrils in group A1 was significantly lower than that in group A5 group,P〈0. 05. After 6 months,the nasal adhesions of group A1 and group A2 were significantly lower than those of A5 group. The rate of posterior nostrils in group A1,group A2 and group A3 was significantly lower than that in A5 group The rate of nasal adhesions and posterior nostrils in A1 group were significantly lower than those in A5 and A4 groups. The nasal adhesions of group A1 were significantly lower than those of A3 Group,P〈0. 05. The rate of nasal adhesions and posterior nostrils in group A was the lowest at 3 months,6 months and 1 year,and the highest in A5 group. Conclusion Endoscopic treatment of acute exudative radiosurgery of nasopharyngeal carcinoma after radiotherapy is effective,which can reduce the secretion of nasal discharge,improve the degree of nasal ventilation,relieve headache,improve nasal adhesions,and reduce nasal cavity narrowing. Of acute infiltration during 1 year follow-up after the onset of radioactive onset of frequency once a week,endoscopic treatmentis the best.
作者
戴如立
邓华瑞
林广明
李湛玲
DAI Rvo-li;DENG Hua-rui;LIN Guang-ming(Guangdong Agricultural Reclation Center Hospital,zhenjiang,Guangdong,524002,Chin)
出处
《黑龙江医学》
2018年第7期745-746,F0003,共3页
Heilongjiang Medical Journal
基金
2014年湛江市科技攻关计划项目(2014B01013)
关键词
急性渗出性放射性鼻炎
鼻内镜
干预时机
频率
Acute exudative radioactive rhinitis
Endoscopic
Intervention time
Frequency
