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加用拉贝洛尔治疗早发型重度子痫前期患者的临床疗效及其对母婴结局的影响 被引量:3

Clinical effect of addtion labetalol in the treatment of early onset severe preeclampsia and its effect on maternal and fetal outcomes
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摘要 目的研究加用拉贝洛尔治疗早发型重度子痫前期患者的临床疗效及其对母婴妊娠结局的影响。方法研究对象选自我院2016年9月至2017年10月收治的94例早发型重度子痫前期患者,采用随机数字法将其分为对照组与观察组,每组47例。对照组给予硫酸镁治疗,在其基础上观察组给予拉贝洛尔治疗。比较两组患者的治疗疗效及不良母婴妊娠结局。结果治疗后,观察组的24 h尿蛋白、收缩压与舒张压均明显低于对照组(P<0.05),观察组不良妊娠结局的总发生率明显低于对照组(P<0.05)。结论加用拉贝洛尔能有效降低早发型重度子痫前期患者的血压,控制患者尿蛋白,改善母婴妊娠结局,值得推广。 Objective To study the clinical efficacy of labetolol in the treatment of early onset severe preeclampsia andits effect on maternal and fetal pregnancy outcomes. Methods Ninety-four cases of early onset severe preeclampsia patientsadmitted in our hospital from September 2016 to October 2017 were selected as the subjects and divided into control groupand observation group according to random number method, with 47 cases in each group. The control group was treatedwith magnesium sulfate, and on the basis of this, the observation group was given labetalol treatment. The curative effectand maternal pregnancy outcome were compared between the two groups. Results After treatment, the 24h urinary protein,systolic pressure and diastolic pressure in the observation group were significantly lower than those in the control group(P〈0.05), the total incidence of adverse pregnancy outcomes in the observation group was significantly lower than that ofthe control group (P〈0.05). Conclusion Addition rabellol can effectively reduce the blood pressure of patients with earlyonset severe preeclampsia, control the urinary protein of patients, improve the outcome of maternal and infant pregnancy,and it is worth promoting.
作者 杨霞 YANG Xia(Shangluo Center Hospital,Shangluo 726000,China)
机构地区 商洛市中心医院
出处 《临床医学研究与实践》 2018年第18期139-140,共2页 Clinical Research and Practice
关键词 拉贝洛尔 早发型重度子痫前期 妊娠结局 labetalol early onset severe preeclampsia pregnancy outcomes
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