摘要
目的:通过分析超微血管成像(SMI)模式下子痫前期(PE)患者胎盘微循环,探讨SMI临床应用价值。方法:应用SMI模式检测孕晚期38例健康孕妇及37例PE患者的胎盘血管,计数单位面积下血管条数(n/cm^2),并检测胎盘中央部最微细动脉的血流动力学参数:搏动指数(PI)、阻力指数(RI)、收缩期最大速度与舒张末期速度之比(S/D)、时间平均流速(TAV),并与超声检查前的最高收缩压、最高舒张压、新生儿出生体重及分娩孕周进行相关性分析。结果:PE组单位面积下血管条数和TAV均低于对照组,差异均有统计学意义(Z=-3.457,P=0.001;Z=-5.199,P=0.000);PE组最微细动脉阻力指标PI、RI、S/D高于对照组,但差异均无统计学意义(P>0.05)。PE组单位面积下血管条数(n/cm^2)与最高收缩压、最高舒张压呈显著负相关(r=-0.369,P<0.01;r=-0.369,P<0.01),与新生儿出生体重及分娩孕周呈显著正相关(r=0.350,P<0.01;r=0.301,P<0.01);TAV与最高收缩压、最高舒张压呈显著负相关(r=-0.556,P<0.01;r=-0.574,P<0.01),与新生儿出生体重及分娩孕周呈显著正相关(r=0.315,P<0.01;r=0.422,P<0.01)。PI、RI、S/D值与最高收缩压、最高舒张压、新生儿出生体重及分娩孕周无显著相关性。结论:SMI模式下单位面积下血管条数及TAV反映PE胎盘微循环变化,具有一定的临床价值。
Objective： To analyze the placental microcirculation in patients with preeclampsia by superb micro-vascular imaging（ SMI） mode and to explore the clinical value of SMI.Methods： Application of superb micro-vascular imaging（ SMI） to detect placental vessels in 38 healthy pregnant women and 37 patients with preeclampsia,count the number of vascular strips per unit area（ n/cm^2）,and to detect the hemodynamic parameters of the central part of the placenta micro artery： pulsatility index（ PI） and resistance index（ RI）,peak systolic velocity and diastolic velocity ratio（ S/D）,time average velocity（ TAV）. Correlation analysis was made between the indexes and the highest systolic pressure,the highest diastolic pressure,neonatal birth weight and gestational weeks of delivery. Results： The number of vascular strips per unit area in preeclampsia group was lower than that in control group,and the difference was significant（ Z =-3.457,P = 0.001）.The TAV of the preeclampsia group was lower than that of the control group,and the difference was significant（ Z =-5. 199,P = 0. 000）. The minimal arterial resistance indexes of PI,RI and S/D in the preeclampsia group were higher than those in the control group,while the differences were not statistically significant（ P 0. 05）. Vascular strips per unit area（ n/cm^2） was significant negatively correlated with the highest systolic pressure and the highest diastolic pressure（ r =-0. 369,P 0. 01; r =-0. 369,P 0. 01）,was significant positively correlated with neonatal birth weight and gestational weeks of delivery（ r = 0.350,P 0.01; r = 0. 301,P 〉0. 01）. TAV was significant negatively correlated with the highest systolic pressure and the highest diastolic pressure（r=-0.556,P〈0.01;r=-0.574,P〈0.01）,was significant positively correlated with neonatal birth weight and gestational weeks of delivery（r=0.315,P〈0.01;r=0.422,P〈0.01）.There was no significant correlation between PI,RI,S/D values and the highest systolic pres
作者
李宁宁
叶玉泉
陈丽娜
王淑霞
唐增军
冯静
王莉
Li Ningning1, Ye Yuquan2,Chen Lina1, et al(1. Department of Obstetrics ; 2. Department of Ultrasound,Hebei General Hospital,Shijiazhuang 05000)
出处
《现代妇产科进展》
CSCD
北大核心
2018年第5期339-342,共4页
Progress in Obstetrics and Gynecology
基金
河北省人社厅引智项目(No:2016051784)
关键词
子痫前期
胎盘
微循环
超微血管成像
血流动力学
Preeclampsia
Placenta
Microcirculation
Superb micro-vascular imaging
Hemodynamics
