摘要
目的探讨七氟醚联合罗库溴铵诱导小儿麻醉对麻醉深度的具体影响和准确性。方法将符合研究条件的气管内插管行七氟醚麻醉患儿40例均分为单药组(单用七氟醚诱导麻醉)和联合用药组(七氟醚联合罗库溴铵诱导麻醉)两组,每组均为20例。比较两组患儿不同时点MAP、HR、NCT、BIS的统计学差异。结果麻醉诱导前两组患儿一般指标的差异均不显著(P>0.05);插管后两组患儿MAP、HR均升高,其差异均具有统计学意义(P<0.05);插管后单药组患儿NCT、BIS显著上升,两组患儿的差异均有统计学意义(P<0.05)。结论单纯七氟醚麻醉诱导时,麻醉深度监测仪能够准确反映气管内插管时麻醉深度的变化,而七氟醚联合罗库溴铵进行麻醉诱导,监测仪则不能准麻醉深度的改变。
Objective To explore the specific effects and accuracy of sevoflurane combined with rocuronium on the depth of anesthesia in children. Methods Forty patients who were eligible as anesthesia patients treated with endotracheal intubation were divided into mono-therapy group（treated with sevoflurane-induced anesthesia only） and combination group（treated with sevoflurane combined with rocuronium-induced anesthesia）,with 20 cases in each group. The statistical differences of MAP,HR,NCT and BIS between two groups at different time points were compared. Results The differences of general indexes between two groups were not significant before anesthesia induction（P〈0. 05）,MAP and HR of the two groups increased significantly after intubation and the differences were both statistically significant（P〈0. 05）. NCT and BIS of the mono-therapy group increased significantly after intubation and the differences were statistically significant（P〈0. 05）. Conclusion When the patients are treated with sevoflurane-induced anesthesia only,the anesthesia depth monitor can accurately reflect the changes in the depth of anesthesia during endotracheal intubation.When the patients are treated with sevoflurane combined with rocuronium-induced anesthesia,the monitor can＇t reflect quasi-anesthesia depth changes.
作者
李泽文
林祥毅
祁贵德
梁惠燕
Li Zewen;Lin Xiangyi;Qi Guide;Liang Huiyan(Women and Children＇s Hospital Affiliated to Guangdong Medical University,Foshan 528300 Chin)
出处
《锦州医科大学学报》
CAS
2018年第3期30-33,共4页
Journal of Jinzhou Medical University
基金
佛山市医学类科技攻关项目
项目编号:2016AB003696
关键词
麻醉深度
七氟醚
罗库溴铵
气管内插管
anesthesia depth
sevoflurane
rocuronium
endotracheal intubation
