摘要
目的:利用双通道技术观察白内障患者超声乳化手术前后、术后使用与不使用聚乙二醇眼液的泪膜变化及其与视觉质量的相关性。方法:将2017年9月至2017年12月在西南医科大学附属医院眼科就诊并行白内障超声乳化术的白内障患者47例分为2组,A组治疗组(22例)术后常规使用妥布霉素地塞米松滴眼液、普拉洛芬滴眼液、聚乙二醇滴眼液,B组对照组(25例)术后使用妥布霉素地塞米松滴眼液、普拉洛芬滴眼液;各组受试对象均于术前、术后1周、术后1月利用眼表综合分析仪检测泪河高度、泪膜破裂时间,并采用基于双通道技术的视觉质量分析系统获取调制传递函数(MTF)截止频率、基础客观散射指数(OSI)及总客观散射指数值(mean OSI),通过计算得出泪膜客观散射指数(TF-OSI)。结果:治疗组术后1周、术后1月的泪膜破裂时间和泪河高度均明显大于对照组,而TFOSI明显小于对照组,差异均具有统计学意义(P<0.05);两组术前OSI值最大,其次是术后1周,术后1月最低,差异具有统计学意义(P<0.05);两组MTF值术前最小,其次是术后1周,术后1月最大,差异均具有统计学意义(P<0.05)。结论:白内障超声乳化术后患者泪膜稳定性较术前差,并显著影响患者视觉质量,人工泪液对此有明显改善,建议术后早期运用人工泪液改善泪膜质量。
Objective：To investigate the change in tear film after cataract phacoemulsification or after the administration of polyethylene glycol eye drops following surgery and its association with visual quality using the dual-channel technique.Methods：A total of 47 patients with cataract who visited Department of Ophthalmology in the Affiliated Hospital of Southwest Medical University from September 2017 to December 2017 and underwent cataract phacoemulsification were enrolled and divided into treatment group with 22 patients and control group with 25patients.The patients in the treatment group were given tobramycin dexamethasone eye drops,pranoprofen eye drops,and polyethylene glycol eye drops after surgery,and those in the control group B were given tobramycin dexamethasone eye drops and pranoprofen eye drops after surgery.Tear meniscus height（TMH）and tear break-up time（TBUT）were measured by an ocular surface analyzer for all patients before surgery and at 1 week and 1 month after surgery.An optical quality analysis system based on the dual-channel technique was used to obtain the cut-off frequency of modulation transfer function,baseline objective scatter index（OSI）,and mean OSI,and OSI of the tear film（TF-OSI）was calculated.TF-OSI was compared between the two groups to clarify the correlation of TF-OSI with other objective indicators of dry eye,and the correlation between the objective indicators of dry eye and visual quality was compared between the groups.Results：Compared with the control group,the treatment group had significantly higher TMH,significantly longer TBUT,and significantly lower TF-OSI at 1 week and 1 month after surgery（P〈0.05）.Both groups had the highest OSI before surgery,which gradually decreased at 1 week after surgery and reached the lowest value at 1 month after surgery（P〈0.05）;both groups had the lowest MTF before surgery,which gradually increased at 1 week after surgery and reached the highest value at 1 month after surgery（P〈0.05）.Conclusion：Patients
作者
邱煜焱
康刚劲
李茂娇
徐曼华
陈映
刘长菊
QIU Yuyan;KANG Gangjing;LI Maojiao;XU Manhua;CHEN Ying;LIU Changju(Department of Ophthalmology,the Affiliated Hospital of Southwest Medical University,Luzhou 646000,Sichuan Province,China)
出处
《西南医科大学学报》
2018年第3期246-250,共5页
Journal of Southwest Medical University
关键词
白内障
超声乳化
泪膜
视觉质量
Cataract
Phacoemulsification
Tearfilm
Visualquality
