摘要
作为眼屈光系统的重要组成部分,角膜组织在眼内压的作用下,受到复杂载荷作用,角膜细胞能够感受力学刺激并做出积极响应。本文通过分析角膜组织的受力情况,综述了力学刺激下角膜细胞的生物学响应及其与角膜损伤修复和相关眼疾患之间的关系。
As an important part of the ocular dioptric system, the corneal tissue is subject to the load under intra-ocular pressure. Corneal cells can sense and respond positively to the mechanical stimulation. In this paper, we review force analysis of corneal tissue borne, biological response of corneal cells to mechanical stimulation, and the relation with the repair after injury and relative diseases.
作者
李晓娜
魏俊超
王晓君
陈维毅
LI Xiaona;WEI Junchao;WANG Xiaojun;CHEN Weiyi(Institute of Applied Mechanics and Biomedical Engineering,Taiyuan University of Technology,Taiyuan 030024,China;Shanxi Key Laboratory of Material Strength & Structural Impact;College of Mechanics,Taiyuan University of Technology,Taiyuan 030024,China 3.National Demonstration Center for Experimental Meehanics Education,Taiyuan University of Technology,Taiyuan 030024,China)
出处
《科技导报》
CAS
CSCD
北大核心
2018年第13期18-22,共5页
Science & Technology Review
基金
山西省重点研发计划国际科技合作项目(201703D421019)
国家自然科学基金项目(11572213)
山西省自然科学基金项目(201701D121144)
关键词
角膜细胞
力学刺激
张应力
切应力
力学生物学
corneal cells
mechanical stimulation
tensile stress
shear stress
mechanobiology