摘要
肿瘤转移是肿瘤相关死亡的主要原因,大量研究显示循环肿瘤细胞(circulating tumor cells,CTCs)在肿瘤转移中起着重要作用。越来越多的研究表明循环肿瘤细胞簇(circulating tumor cells clusters,CTC clusters)与单循环肿瘤细胞相比转移能力更强。分离检测技术的不断进步为深入研究循环肿瘤细胞簇提供了便利。本文就循环肿瘤细胞簇在肿瘤转移中的研究进展作一综述。
Tumor metastasis is the main cause of tumor related death.A large number of studies show that circulating tumor cells (CTCs) play an important role in tumor metastasis.Recently,more and more studies have shown that circulating tumor cell clusters (CTC clusters) are more metastatic than single circulating tumor cell.The continuous progress of separation and detection technology is convenient for in-depth study of circulating tumor cell clusters.In this paper,the progress of CTC clusters in tumor metastasis is reviewed.
作者
石新林
徐兴祥
Shi Xinlin;Xu Xingxiang(Department of Respiration,Yangzhou University Medical Academy,Jiangsu Yangzhou 225001,China)
出处
《现代肿瘤医学》
CAS
2018年第16期2639-2642,共4页
Journal of Modern Oncology
关键词
循环肿瘤细胞簇
肿瘤转移
研究进展
circulating tumor cell clusters
tumor metastasis
reaserch progress