期刊文献+

循环肿瘤细胞簇在肿瘤转移中的研究进展 被引量:2

Research progress of circulating tumor cell clusters in tumor metastasis
下载PDF
导出
摘要 肿瘤转移是肿瘤相关死亡的主要原因,大量研究显示循环肿瘤细胞(circulating tumor cells,CTCs)在肿瘤转移中起着重要作用。越来越多的研究表明循环肿瘤细胞簇(circulating tumor cells clusters,CTC clusters)与单循环肿瘤细胞相比转移能力更强。分离检测技术的不断进步为深入研究循环肿瘤细胞簇提供了便利。本文就循环肿瘤细胞簇在肿瘤转移中的研究进展作一综述。 Tumor metastasis is the main cause of tumor related death.A large number of studies show that circulating tumor cells (CTCs) play an important role in tumor metastasis.Recently,more and more studies have shown that circulating tumor cell clusters (CTC clusters) are more metastatic than single circulating tumor cell.The continuous progress of separation and detection technology is convenient for in-depth study of circulating tumor cell clusters.In this paper,the progress of CTC clusters in tumor metastasis is reviewed.
作者 石新林 徐兴祥 Shi Xinlin;Xu Xingxiang(Department of Respiration,Yangzhou University Medical Academy,Jiangsu Yangzhou 225001,China)
机构地区 扬州大学医学院
出处 《现代肿瘤医学》 CAS 2018年第16期2639-2642,共4页 Journal of Modern Oncology
关键词 循环肿瘤细胞簇 肿瘤转移 研究进展 circulating tumor cell clusters tumor metastasis reaserch progress
  • 相关文献

参考文献1

二级参考文献97

  • 1Behrens J, Lowrick O, Klein-Hitpass L, Birchmeier W. The Ecadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element. Proc Natl Acad Sci USA 1991, 88:11495-11499 被引量:1
  • 2Birchmeier W, Behrens J, Weidner KM, Frixen UH, Schipper J. Dominant and recessive genes involved in tumor cell invasion. Curr Opin Cell Biol 1991, 3:832-840 被引量:1
  • 3Giroldi LA, Bringuier PP, de Weijert M, Jansen C, van Bokhoven A, Schalken JA. Role of E boxes in the repression of E-cadherin expression. Biochem Biophys Res Commun 1997, 241:453-458 被引量:1
  • 4Hajra KM, Ji X, Fearon ER. Extinction of E-cadherin expression in breast cancer via a dominant repression pathway acting on proximal promoter elements. Oncogene 1999, 18:7274-7279 被引量:1
  • 5Ji X, Woodard AS, Rimm DL, Fearon ER. Transcriptional defects underlie loss of E-cadherin expression in breast cancer. Cell Growth Differ 1997, 8:773-778 被引量:1
  • 6Karreth F, Tuveson DA. Twist induces an epithelial-mesenchymal transition to facilitate tumor metastasis. Cancer Biol Ther 2004, 3: 1058-1059 被引量:1
  • 7Thiery JE Morgan M. Breast cancer progression with a Twist. Nat Med 2004, 10:777-778 被引量:1
  • 8Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002, 2:563-572 被引量:1
  • 9Pantel K, Brakenhoff RH. Dissecting the metastatic cascade. Nat Rev Cancer 2004, 4:448-456 被引量:1
  • 10MacDonald IC, Groom AC, Chambers AF. Cancer spread and micrometastasis development: quantitative approaches for in vivo models. Bioessays 2002, 24:885-893 被引量:1

共引文献56

同被引文献20

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部