摘要
目的 :了解幽门螺杆菌 (hehicobacterpylori,HP)感染与门脉高压性胃病 (portalhypertensivegastropathy,PHG)的发病关系。方法 :选门脉高压性胃病患者胃窦黏膜 2 6例 ,免疫组化SP法 (链霉菌抗生物素蛋白 -过氧化酶法 ,Streplavidin Peroxidase ,SP)抗HP抗体染色 ,并以慢性乙型肝炎并胃炎 1 8例及非肝病性胃病 2 1例胃窦黏膜作对照。结果 :2 6例门脉高压性胃病阳性 1 8例 (69.2 % ) ;1 8例慢乙肝组阳性 1 0例 (55 .5 % ) ;2 1例非肝病组阳性 1 1例 (52 .3% )。门脉高压组HP感染阳性率与慢乙肝组、非肝病组相比差异无显著性 (P >0 .0 5) 。结论 :HP感染虽不是门脉高压性胃病的发生原因 ,但在治疗中短期加用杀HP的药物是必要的。
Objective: To study the relationship between portal hypertensive gastropathy and HP infection. Methods: The gastric antrum mucosa of 26 cases with portal hypertensive gastropathy were selected. Through immunohistochemical SP method, the mucosa was stained by anti HP antibody. The gastric antrum mucosa of 18 cases with chronic hepatitis B complicated with gastropathy and 21 cases with non hepatic gastropathy were selected as controls. Results: There are 18 cases with positive HP infection in these 26 cases with portal hypertensive gastropathy (69.2%); there are 10 cases with positive HP infection in those 18 cases with chronic hepatitis B complicated with gastropathy (55.5%); there are 11 cases with positive HP infection in those 21 non hepatic gastropathy (52.3%).There are no absolute difference (p>0.05) of the positive HP infection among portal hypertensive gastropathy, chronic hepatitis B complicated with gastropathy,and non-hepatic gastropathy. Conclusion: Although the HP infection is not the cause that induces the portal hypertensive gastropathy, it is necessary to take the killing HP drugs in short time during the treatment of portal hypertensive gastropathy. [
出处
《沈阳医学院学报》
2002年第3期137-139,共3页
Journal of Shenyang Medical College
关键词
门脉高压性胃病
免疫组化SP法
幽门螺杆菌感染
portal hypertensive gastropathy
hylicobacter pylori
immunohistochemical SP method
