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原发性胆汁性肝硬化发病机制研究进展 被引量:19

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摘要 原发性胆汁性肝硬化(Prmary biliary crrhosis,PBC)以破坏肝内小及中等大小胆管为主的器官特异性自身免疫性肝病,表现为肝门脉区炎症导致纤维化,肝硬化甚至功能性衰竭.PBC患者90%以上为女性,年龄一般为30至65岁之问.自身免疫病可见少儿患者,但PBC是唯一例外,随年龄增长期发病率呈上升趋势.
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2002年第8期586-589,共4页 Chinese Journal of Immunology
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