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多排螺旋CT与MRI对乙型肝炎肝硬化背景小肝癌检出的比较研究 被引量:16

Comparative study of multi-slice spiral CT and MRI in detection of small hepatocellular carcinoma in patients with hepatitis B cirrhosis
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摘要 目的:比较多排螺旋计算机断层扫描(CT)与磁共振成像(MRI)对乙型肝炎肝硬化背景小肝癌的检出准确性和诊断价值。方法:将2014年1月~2016年12月我院收治的120例乙型肝炎肝硬化背景疑似小肝癌患者纳入研究,所有患者均接受多排螺旋CT和MRI检查,分析多排螺旋CT和MRI检查结果,以手术病理诊断结果为金标准,计算和比较多排螺旋CT、MRI对乙型肝炎肝硬化背景小肝癌的诊断灵敏度、特异度、准确性。根据手术病理诊断结果,将确诊乙型肝炎肝硬化背景小肝癌按照病灶直径分为微小肝癌(<1cm)和小肝癌(1~3cm),比较CT、MRI对不同大小病灶的检出情况。结果:120例纳入病例中,共有88例患者经手术病理诊断确诊为乙型肝炎肝硬化背景小肝癌,包括35例微小肝癌、53例小肝癌。经计算,MRI对乙型肝炎肝硬化背景小肝癌的诊断灵敏度、特异度、准确性分别为96.59%、96.88%、96.67%,均高于CT诊断的86.36%、75.00%、83.33%(P<0.05)。MRI对微小肝癌、小肝癌的诊断符合率分别为97.14%、96.23%,均明显高于CT诊断的80.00%、81.13%(P<0.05)。结论:相比于多排螺旋CT,采用MRI对乙型肝炎肝硬化背景小肝癌的诊断灵敏度、特异度和准确性均更加优越,可有效检出微小肝癌病灶。 Objective :To study and compare the multi row spiral computed tomography (Computed tomography, CT)and magnetic reso- nance imaging (Magnetic resonance, imaging, MRI)detection accuracy and diagnostic value of hepatitis B cirrhosis background of small hepa- tocellular carcinoma. Methods:from January- 2014 - December 2016 period, 120 cases of suspected hepatitis B cirrhosis patients with small hepatocellular carcinoma in our hospital during the period of time in total were into as the object of study, all patients received multi - slice spiral CT examination, MRI examination, analysis of multi slice spiral CT and MRI examination results, surgical pathological diagnosis as the gold standard, calculation and comparison of multi slice spiral CT, diagnostic sensitivity, MRI on the background of hepatitis B cirrhosis of small HCC specificity and accuracy. According to the results of biopsy, the diagnosis of hepatitis B cirrhosis background of small hepatocellular carcinoma according to the diameter of the lesion is divided into small hepatocellular carcinoma ( 〈 1 era) and small liver Cancer ( 1 - 3cm), CT, MRI detection of different sizes of lesions. Results : 120 cases of suspected cases, a total of 88 patients pathologically diagnosed as hepatitis B cirrhosis background of small hepatocellular carcinoma,including 35 cases of small hepatocellular carcinoma,53 cases of small hepatocellu- lar carcinoma. Through calculation, the diagnostic sensitivity-, MRI of hepatitis B liver cirrhosis background of small HCC specificity and accu- racy were 96.59% ,96.88% ,96.67%,were higher than CT in the diagnosis of 86.36% ,75%,83.33% (P 〈 0.05 ). M RI on small hepato- cellular carcinoma,97.14% respectively, consistent with the diagnosis of small hepatocellular carcinoma 96.23 % , were significantly higher than that of CT in the diagnosis of 80% ,81.13 % ( P 〈 0.05 ). Conclusion : compared in multi slice spiral CT, the diagnostic sensitivity- of MRI on the background of hepatitis B cirrhosis of s
出处 《中西医结合肝病杂志》 CAS 2018年第4期204-206,共3页 Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金 珠海市科技计划相关项目(No.2015A0011)
关键词 乙型肝炎肝硬化背景小肝癌 诊断 多排螺旋CT MRI hepatitis B cirrhosis background small liver cancer diagnosis multi slice spiral CT MRI
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