摘要
目的观察丹红注射液治疗不稳定型心绞痛的临床效果。方法将我院收治的79例不稳定型心绞痛患者随机分为对照组(n=39,硝酸甘油治疗)和观察组(n=40,硝酸甘油+丹红注射液治疗)。比较两组的治疗效果。结果观察组治疗总有效率高于对照组(P<0.05)。治疗后,两组ANP、NO及ET水平均明显改善,且观察组优于对照组(P<0.05)。治疗后,两组IL-6及TNF-α水平均明显降低,且观察组低于对照组(P<0.05)。两组患者均未见不良反应发生。结论丹红注射液联合硝酸甘油可以有效降低炎性,提高NO和APN水平,改善血管内皮功能,疗效安全,值得临床推广应用。
Objective To analyze the clinical effect of Danhong injection on patients with unstable angina pectoris.Methods A total of 79 patients with unstable angina pectoris treated in our hospital were randomly divided into control group（n=39, treated with nitroglycerin） and observation group （n=40, treated with nitroglycerin＋Danhong injection）. The treatmenteffects of both groups were compared. Results The total effective rate of treatment in the observation group was higher thanthat in the control group （P〈0.05）. After treatment, the levels of ANP, NO and ET significantly improved in the two groups,and those of the observation group were superior to the control group（P〈0.05）. After treatment, the levels of IL-6 and TNF-琢in the two groups significantly decreased, and those of the observation group were lower than the control group （P〈0.05）. Noadverse reactions occurred in both groups. Conclusion Danhong injection combined with nitroglycerin can reduceinflammation, improve the levels of NO and APN effectively, improve the function of vascular endothelial, with safe efficacy,which is worthy of clinical popularization and application.
作者
李凯
LI Kai(the Hospital of Xunyang County,Ankang 725700,Chin)
出处
《临床医学研究与实践》
2018年第21期111-112,共2页
Clinical Research and Practice
