摘要
检测血浆N末端前体脑钠肽(NT-proBNP)值来判断小儿脓毒症的病情及预后的临床意义。选取本院儿童重症监护病房(PICU)的37例住院病人,均诊断为脓毒症(Sepsis),并记录小儿危重症(PCIS)评分、小儿死亡危险因素(PRISMⅢ)评分,依病情严重程度分为脓毒症组22例和脓毒性休克组15例,进行对比血浆NTproBNP、降钙素原(PCT)值、预后关系;结果发现脓毒性休克组、死亡组PRISMⅢ及血浆NT-proBNP、PCT值明显升高,PCIS明显降低;根据患儿血浆NT-proBNP值可判断及评估小儿脓毒症的病情严重程度及预后,有利于指导临床早期实施有效干预措施。
Detection of plasma N terminal pro brain natriuretic peptide（ NT-pro BNP） value was used to determine the clinical significance and prognosis of sepsis in children. 37 hospitalized patients in our pediatric intensive care unit（ PICU） were selected. All of them were diagnosed as sepsis（ Sepsis）,and the score of children＇s critical disease（ PCIS）and the risk factors of child death（ PRISM III） score were recorded. According to the severity of illness,22 cases of sepsis group and 15 cases of septic shock（ Septic shock） group were divided into two groups,to compare plasma NT-pro BNP,PCT value and prognosis.The results showed that the levels of PRISM III and NT-pro BNP and PCT in septic shock group and death group increased significantly,while PCIS decreased significantly. According to the plasma NT-pro BNP value of children,the severity and prognosis of sepsis in children can be determined and evaluated,which is conducive to guiding early clinical implementation of effective intervention measures.
作者
张红艳
欧元香
赖源
ZHANG Hongyan;OU Yunxiang;LAI Yuan(The Third Hospital of Changsha,Changsha 410015,Hunan,China)
出处
《中南医学科学杂志》
CAS
2018年第4期385-387,共3页
Medical Science Journal of Central South China
