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曼月乐与米非司酮治疗围绝经期功血的临床疗效与安全性比较 被引量:3

Comparison of effects and safety of Mirena and Mifepristone in treatment of perimenopausal dysfunctional uterine bleeding
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摘要 目的:比较围绝经期功血采用曼月乐与米非司酮治疗的临床效果。方法:选择2016年9月至2017年9月漯河市郾城区人民医院收治的围绝经期功血患者150例,使用随机数表法将所有患者分为两组,各75例。对照组给予米非司酮治疗,观察组采用曼月乐治疗,比较两组临床疗效、不良反应、子宫内膜厚度、经期与血红蛋白水平。结果:观察组临床疗效(93.99%)高于对照组(68.00%),观察组不良反应发生率(9.33%)低于对照组(29.33%),差异均有统计学意义(P<0.05);治疗后观察组患者子宫内膜厚度、经期均少于对照组,血红蛋白水平高于对照组,差异均有统计学意义(P<0.05)。结论:曼月乐治疗围绝经期功血的临床效果与安全性优于米非司酮。 Objective: To compare clinical effects of Mirena and Mifepristone in treatment of perimenopausal dysfunctional uterine bleeding. Methods: From September 2016 to September 2017,150 cases of perimenopausal dysfunctional uterine bleeding in Yancheng district people's hospital were selected and divided into 2 groups,75 cases in each. The control group was given Mifepristone treatment,while the observation group was treated with Mirena. The clinical effects,adverse reactions,endometrial thickness,menstrual period and hemoglobin levels of the two groups were compared. Results: The clinical effective rate of the observation group( 93.99%) was higher than that of the control group( 68.00%),the incidence rate of adverse reaction( 9.33%) was lower than that of the control group( 29.33%),and the differences was statistically significant( P〈0.05). After the treatment,the endometrial thickness and the menstrual period of the observation group were less than those of the control group,the hemoglobin level was higher than that of the control group,and the differences were statistically significant( P〈0.05). Conclusions: Mirena in the treatment of perimenopausal dysfunctional uterine bleeding is more effective than Mifepristone.
作者 赵丽平 ZHAO Liping(Yancheng Distriet People's Hospital,Luohe Henan463200,Chin)
出处 《中国民康医学》 2018年第9期33-34,42,共3页 Medical Journal of Chinese People’s Health
关键词 围绝经期功血 曼月乐 米非司酮 效果 Perimenopausal dysfunctional uterine bleeding Mirena Mifepristone Effect
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